Investigation of the genomic determinants of childhood leukemia using next-generation sequencing

使用下一代测序研究儿童白血病的基因组决定因素

• 批准号: 201982
• 负责人: Sinnett Daniel
• 金额: $ 47.14万
• 依托单位: Centre hospitalier universitaire Sainte-Justine (Montral, Qubec)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-03-01 至 2015-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=201982&lang=en
• 关键词: Bioinformatics; Biostatistics; Cancer Genomics; Childhood Leukemia; Epigenetics; Functional Analysis; Next-Generation Sequencing; Snp Arrays

Acute lymphoblastic leukemia (ALL) is the most frequent cancer in children, accounting for approximately 25% of all pediatric tumors. We have previously shown that the origins of childhood leukemia could be explained by a combination of genetic and enviro

急性淋巴细胞白血病（ALL）是儿童中最常见的癌症，约占所有儿科肿瘤的25%。我们先前已经表明，儿童白血病的起源可以用遗传和环境因素的结合来解释。