Industry/University Cooperative Project: Polarity of Super- critical Fluid Solvents

目的是预测超临界流体(SF)溶剂极性对萃取选择性和反应速率常数的热力学影响。超临界流体的极性是用吸收在UV-可见光区域的染料探针用光谱学测量的。特定相互作用的强度，如氢键，在很大的压力范围内进行测量，以识别高度选择性的纯和二元超临界溶剂。显微光谱数据将用于解释甾醇和其他溶质的选择性数据。本项目所获得的光谱数据可用于设计用于分离过程的高选择性混合超临界流体溶剂，以及基于热动力学溶剂效应的超临界流体中潜在的新反应过程的评估。

The objective is to predict the thermodynamic effects of the polarity of supercritical fluid (SF) solvents on extraction selectivities and reaction rate constants. The polarity of supercritical fluids is measured spectroscopically, using dye probes that absorb in the UV-visible region. The strength of specific interactions, such as hydrogen bonding, is measured over a wide range in pressure to identify highly selective pure and binary supercritical solvents. The microscopic spectroscopic data will be used to interpret the selectivity data for sterols and other solutes. The spectroscopic data obtained in this project can be used to design highly selective mixed supercritical fluid solvents for separation processes, and to evaluate potential new reaction processes in supercritical fluids based on the thermodymanic solvent effect.