Evaluation of synaptic scaling in Huntington disease mice

亨廷顿病小鼠突触缩放的评估

• 批准号: 311804
• 负责人: Smith-Dijak Amy I
• 金额: $ 1.27万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-12-01 至 2014-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=311804&lang=en
• 关键词: Ampa Receptor; Homeostatic Plasticity; Huntington Disease; Neurodegeneration; Neuroscience; Nmda Receptor; Physiology; Plasticity; Striatum; Synaptic Scaling

Huntington disease is a genetic disorder caused by the inheritance of at least one mutated version of the huntingtin gene. Age of onset of Huntington disease is typically from the mid thirties to the late fourties, with motor, psychiatric and cognitive sy

亨廷顿病是一种遗传性疾病，由亨廷顿基因的至少一种突变形式遗传引起。亨廷顿舞蹈病的发病年龄通常为30多岁至40多岁，运动、精神和认知系统均出现异常。