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Validation of a glycerolipid/ free fatty acid cycling enzyme as a novel therapeutic target for type-2 diabetes

Validation of a glycerolipid/ free fatty acid cycling enzyme as a novel therapeutic target for type-2 diabetes
验证甘油脂/游离脂肪酸循环酶作为 2 型糖尿病的新治疗靶点
批准号：
227905
负责人：
Prentki Marc
金额：
$11.5万
依托单位：
Centre hospitalier de l'Universit de Montral (CHUM)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2011
资助国家：
加拿大
项目状态：
已结题
起止时间：
2011-02-01 至 2012-02-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=227905&lang=en
关键词：
Drug Development Insulin Secretion Monoglyceride Lipase Pancreatic Beta Cell Type-2 Diabetes

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英文摘要
Type-2 diabetes affects nearly 300 million people worldwide with a staggering $3 trillion in associated health costs in North America alone. Unfortunately, currently available drugs lack long-term effectiveness and need to be used in combination of 2 or m
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Glycerol 3-phosphate phosphatase and the glycerol shunt in senescence and healthy aging
The glycerol shunt and nutrient excess detoxification in the pancreatic ß-cell and liver
Lipid metabolism, insulin secretion and energy homeostasis
Symposium on Cardiometabolic diseases of the Montreal Diabetes Research Center
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