Characterization and Manipulaton of Protein Structure- Function Relationships for Bioprocess Application
Characterization and Manipulaton of Protein Structure- Function Relationships for Bioprocess Application
批准号:
8606179
负责人:
James Bailey
金额:
$31.68万
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
1986
资助国家:
美国
项目状态:
已结题
起止时间:
1986-09-01 至 1990-02-28
中文摘要
该项目将扩大对生物过程中蛋白质的理解,其中蛋白质受到与其原生生物环境截然不同的环境的影响。对固定化酶或结合抗体吸附剂的加工特性的仔细研究,将与这种蛋白质的分子结构探针相协调。这些基本结构探针为了解固定化蛋白的配方、使用条件和功能特性之间的联系提供了关键的环节。所有这些研究都将在一个使用数学建模来协助解释和组织数据的环境中进行。
英文摘要
This project will expand the understanding of proteins in bioprocesses where there proteins are subjected to environments much different from their native biological milieu. Careful investigations of the processing properties of an immobilized enzyme or bound antibody sorbent are to be coordinated with probes of the molecular configuration of such a protein. These fundamental structural probes provide a crucial link for understanding the connections among formulation, use conditions, and functional characteristics of immobilized proteins. All of this research will be conducted in an environment which employs mathematical modeling to assist in interpreting and organizing the data.
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Concurrent Engineering Protocols and Project Management, Phase II
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批准号:9414273
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项目类别:Continuing Grant
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资助金额:$21.78万
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财政年份:1994
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负责人:James Bailey
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依托单位:
Concurrent Engineering Protocols and Project Management
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批准号:9215514
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项目类别:Standard Grant
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资助金额:$5.09万
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财政年份:1992
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负责人:James Bailey
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依托单位:
Kinetics of Intracellular Protein Degradation in Bacteria
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批准号:8721973
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项目类别:Continuing Grant
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资助金额:$27.28万
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财政年份:1988
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负责人:James Bailey
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依托单位:
Assessing and Manipulating Single-Cell Productivity in Recombinant Cell Populations
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批准号:8805636
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项目类别:Continuing Grant
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资助金额:$38.98万
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财政年份:1988
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负责人:James Bailey
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依托单位:
Engineering Research Equipment Grant: Equipment for Construction and Characterization of Recombinant Microorganisms
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批准号:8607589
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项目类别:Standard Grant
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资助金额:$4.36万
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财政年份:1986
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负责人:James Bailey
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依托单位:
Immobilized Cell Bioconversion Catalysis: Manipulation and Monitoring of Activity, Selectivity, and Stability
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批准号:8604408
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项目类别:Continuing Grant
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资助金额:$23.54万
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财政年份:1986
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负责人:James Bailey
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依托单位:
Process Dynamic Models for Heterogeneous Catalysis of Oxidation and Hydrogenation Reactions
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批准号:8419846
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项目类别:Continuing Grant
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资助金额:$19.28万
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财政年份:1985
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负责人:James Bailey
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依托单位:
Macromolecular Synthesis and Growth Properties of Plasmid- Carrying Microorganisms
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批准号:8501656
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项目类别:Standard Grant
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资助金额:$29.15万
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财政年份:1985
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负责人:James Bailey
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依托单位:
U.S.-Japan Workshop in Biotechnology/Bioreactors/Kyoto, Japan/December 1985
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批准号:8602418
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项目类别:Standard Grant
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资助金额:$0.0万
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财政年份:1985
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负责人:James Bailey
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依托单位:
U.S.-Japan Workshops in Biotechnology Under the Mori Initiative
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批准号:8519652
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项目类别:Standard Grant
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资助金额:$0.0万
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财政年份:1985
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负责人:James Bailey
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依托单位:
Measuring, Modeling, and Maximizing Product Formation in Segregated Microbial Populations
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批准号:8312527
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项目类别:Continuing Grant
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资助金额:$30.06万
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财政年份:1983
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负责人:James Bailey
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依托单位:
Structure-Function Relationships in Immobilized Enzyme Catalysis
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批准号:8213551
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项目类别:Continuing Grant
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资助金额:$13.39万
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财政年份:1983
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负责人:James Bailey
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依托单位:
Characterization and Optimization of Product Expression in Recombinant Bacteria
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批准号:8118425
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项目类别:Continuing Grant
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资助金额:$23.41万
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财政年份:1982
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负责人:James Bailey
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依托单位:
Process Dynamic Models For Heterogeneous Catalysts
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批准号:8111607
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项目类别:Continuing Grant
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资助金额:$21.82万
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财政年份:1981
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负责人:James Bailey
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依托单位:
Studies of the Dynamics of Individual Cells and Microbial Populations
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批准号:8011454
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项目类别:Continuing Grant
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资助金额:$18.29万
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财政年份:1980
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负责人:James Bailey
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依托单位:
Studies of Forced Dynamic Behavior of Catalytic Reactors
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批准号:8019606
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项目类别:Continuing Grant
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资助金额:$5.17万
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财政年份:1980
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负责人:James Bailey
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依托单位:
Immobilization of Enzymes in Insoluble Porous Materials
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批准号:7825154
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项目类别:Standard Grant
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资助金额:$12.19万
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财政年份:1979
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负责人:James Bailey
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依托单位:
Studies of Forced Dynamic Behavior of Catalytic Reactors
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批准号:7817723
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项目类别:Continuing Grant
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资助金额:$11.37万
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财政年份:1978
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负责人:James Bailey
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依托单位:
Structured Population Dynamics in Microbial Process Systems
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批准号:7709592
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项目类别:Standard Grant
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资助金额:$7.0万
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财政年份:1977
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负责人:James Bailey
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依托单位:
Periodic Operation of Chemical Reactors: Experimental Investigations and Theoretical Development
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批准号:7609000
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项目类别:Standard Grant
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资助金额:$9.62万
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财政年份:1976
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负责人:James Bailey
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依托单位: