An Assessment of Computed Tomography and Related Technology as an Improved Means of Characterizing Bone Structure

计算机断层扫描及相关技术作为表征骨结构的改进方法的评估

• 批准号: 8660319
• 负责人: Donna Smith
• 金额: $ 3.89万
• 依托单位: PDA Engineering
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-02-01 至 1987-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8660319&HistoricalAwards=false
• 关键词: Assessment; Computed; Tomography; Related; Technology

The problems of assessing the deterioration of musculoskeletal functions in a human after disease or excessive loads, continues to be a social problem of enormous magnitude. Major advances in computerized axial tomography (CAT) scanning during the past decade has provided an effective means to spatially and quantitatively examine the internal structure of parts of the body. CAT scan images are interpreted to provide information for improved diagonistic procedures and treatments. Further advances in the CAT scan method appear possible by utilizing image analysis methods to quantatively evaluate the CAT scan images. The research program deals with developing software for image analysis to establish a quantitative method for evaluating bone structure, density and geometry of the human musculoskeletal system. Specifically the project will focus on osteoporosis femur specimens with the objective of evaluating the extent and severity of the disease. Physical and mechanical property evaluation will also be performed to correlate CT data with important mechanical properties. PDA Engineering has an excellent background in R&D associated with both industrial and medical CT scanner systems and have significant experience in biomedical applications. The staff qualifications are excellent as the research team has extensive experience in electronics, NDE and bioengineering which are required for successful completion of the program. A grant is recommended.

评估肌肉骨骼功能恶化的问题 在人类患病或过度负荷后， 巨大的问题。 计算机轴向控制的主要进展 在过去的十年中，断层扫描（CAT）扫描提供了一个 有效的手段，空间和定量研究内部 身体各部分的结构。 CAT扫描图像被解释为 为改进诊断程序和治疗提供信息。 CAT扫描方法的进一步发展似乎是可能的， 图像分析方法对CAT扫描图像进行定量评价。 该研究计划涉及开发图像分析软件 建立一种定量评价骨结构的方法， 密度和人体肌肉骨骼系统的几何形状。 具体 该项目将重点研究骨质疏松症股骨标本， 目的是评估疾病的范围和严重程度。 还将进行物理和机械性能评价， 将CT数据与重要的机械性能相关联。 PDA工程在研发方面有着出色的背景， 工业和医疗CT扫描仪系统，并具有重要的 生物医学应用经验。 工作人员的资格是 优秀的研究团队在电子领域拥有丰富的经验， NDE和生物工程，这是成功完成 节目 建议提供赠款。