Fluorinated Ring and Acyclic Compounds of Groups 15 and 16 -Their Syntheses and Reactions

第 15 族和第 16 族氟化环和无环化合物 - 它们的合成和反应

• 批准号: 8703790
• 负责人: Jean'ne Shreeve
• 金额: $ 19.7万
• 依托单位: Regents of the University of Idaho
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-04-15 至 1990-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8703790&HistoricalAwards=false
• 关键词: Fluorinated; Ring; Acyclic; Compounds; Groups

Further research on the preparation and properties of fluorine compounds is important because the presence of one or more fluorine atoms or fluorinated groups in molecules has a marked effect on the chemical and physical properties as well as on the biological activity of these materials. The substitution of fluorine for other atoms in a compound often leads to profound increases in resistance to thermal degradation or decomposition in water. These drastic differences in properties are seen in comparing polyethylene, which does not contain fluorine, to teflon, which does contain fluorine. The research will involve the syntheses and characterization of a wide variety of fluorine-containing nitrogen, sulfur and phosphorus compounds in an effort to either modify characteristics of previously known compounds or to develop entirely new families of compounds that may have many applications, e.g., as thermally and hydrolytically stable polymers, as plant growth inhibitors, as muscle relaxants, or as anticonvulsants, in addition to providing much useful basic information when fluorinated and nonfluorinated analogs are studied concurrently. This study will provide other researchers with information about thermodynamic and kinetic stabilities, properties, structures and bonding as well as methods of synthesis of a diverse collection of compound types. All new materials will be characterized via infrared, Raman, nuclear magnetic resonance and mass spectra and elemental analyses. Many will be submitted for biological testing and some for structural studies.

氟的制备及性质的进一步研究 化合物是重要的，因为存在一个或多个氟 分子中的原子或氟化基团对 化学和物理性质以及生物活性 这些材料。 氟原子取代氟原子中的其他原子 复合物通常导致耐热性的显著增加， 在水中降解或分解。 这些巨大的差异， 在比较聚乙烯中可以看出，聚乙烯不含 从氟到含氟的碲。 这项研究将涉及广泛的合成和表征 各种含氟氮、硫、磷 化合物，以努力改变以前的特征， 已知的化合物或开发全新的化合物家族， 可以具有许多应用，例如，由于热和水解 稳定的聚合物，作为植物生长抑制剂，作为肌肉松弛剂，或作为 抗惊厥药，除了提供许多有用的基本信息， 当同时研究氟化和非氟化类似物时。 这项研究将为其他研究人员提供以下信息： 热力学和动力学稳定性、性质、结构和 键合以及各种合成方法， 复合类型。 所有新材料都将通过红外线进行表征， 拉曼、核磁共振和质谱以及元素分析 分析。 许多将提交生物测试，一些将提交 结构研究。