Acquisition of a Mass Spectrometer and Upgrading of FAB-MS Capabilities

质谱（MS）技术，例如电子轰击（EI）和 快原子轰击（FAB）用于探测亲密的 结构细节，并获得分子组成 大量的有机的，生物有机的，和有机金属的 分子。 购置能够 执行这些最先进的技术是必不可少的 在若干领域进行前沿研究， 化学. 购买一台新的质谱仪， FAB-MS的能力将得到 化学共享仪器计划和生物 仪表计划。研究的主要领域， 加强的措施包括： 1)磷腈化学 2)大鼠α-1酸的糖基化位点分析 糖蛋白 3)蝶呤化学 4)毛细管区带质谱 5)模板控制的低聚反应 6)合成有机金属化学

Mass spectral (MS) techniques such as Electron Impact (EI) and Fast Atom Bombardment (FAB) are used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic, and organometallic molecules. The acquisition of instrumentation capable of carrying out these state-of-the-art techniques is essential for the prosecution of frontier research in several fields of chemistry. The purchase of a new mass spectrometer and the upgrading of FAB-MS capabilities will be facilitated by support from the Chemistry Shared Instrumentation Program and the Biological Instrumentation Program. The major areas of research that will be enhanced include: 1) The chemistry of phosphazenes 2) Glycosation-site analysis of rat alpha-1 acid glycoprotein 3) Chemistry of pterins 4) Capillary zone electrophoresis-mass spectrometry 5) Template controlled oligomerizations 6) Synthetic organometallic chemistry