U.S.-Japan Cooperative Research: Regulation of Heat Shock Response in E. coli

美日合作研究：大肠杆菌热激反应的调节

• 批准号: 8716439
• 负责人: Carol Gross
• 金额: $ 2.47万
• 依托单位: University of Wisconsin-Madison
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-03-15 至 1991-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8716439&HistoricalAwards=false
• 关键词: U.S.; Japan; Cooperative; Research; Regulation

This award will enable Dr. Carol A. Gross of the University of Wisconsin to collaborate with Professor Takashi Yura of Kyoto University, Japan on the study of heat shock response in Escherichia coli. They will investigate the regulatory mechanism of this organism's response to exposure to high temperature. Heat shock response appears to be similar in most organisms, and thus an understanding of the regulatory mechanism of this response in E. coli could be of fundamental biological significance. Dr. Gross has applied biochemical and physiological techniques to the study of heat shock response, while Dr. Yura has been pursuing a genetic approach. A collaborative study incorporating these complementary approaches is timely.

该奖项将使威斯康星大学的 Carol A. Gross 博士能够与日本京都大学的 Takashi Yura 教授合作研究大肠杆菌的热休克反应。 他们将研究这种生物体对暴露于高温的反应的调节机制。 大多数生物体的热休克反应似乎相似，因此了解大肠杆菌中这种反应的调节机制可能具有基本的生物学意义。 Gross 博士将生物化学和生理学技术应用于热休克反应的研究，而 Yura 博士则一直在寻求基因方法。 结合这些互补方法的合作研究是及时的。