U.S.-Japan Cooperative Research: Regulation of Heat Shock Response in E. coli

该奖项将使卡罗尔博士。格罗斯大学 威斯康星州与京都的Yura教授合作 日本大学关于大肠杆菌热休克反应的研究 杆菌 他们将调查这方面的监管机制 有机体对高温的反应。 热休克反应在大多数生物体中似乎是相似的， 从而了解这种反应的调节机制 在大肠大肠杆菌的基因可能具有重要的生物学意义。 格罗斯博士应用生物化学和生理学技术， 热休克反应的研究，而尤拉博士一直在追求一个 遗传方法。 一项合作研究将这些 互补的方法是及时的。

This award will enable Dr. Carol A. Gross of the University of Wisconsin to collaborate with Professor Takashi Yura of Kyoto University, Japan on the study of heat shock response in Escherichia coli. They will investigate the regulatory mechanism of this organism's response to exposure to high temperature. Heat shock response appears to be similar in most organisms, and thus an understanding of the regulatory mechanism of this response in E. coli could be of fundamental biological significance. Dr. Gross has applied biochemical and physiological techniques to the study of heat shock response, while Dr. Yura has been pursuing a genetic approach. A collaborative study incorporating these complementary approaches is timely.