Purchase of a 300 MHz Wide Bore NMR Spectrometer

核磁共振波谱是化学家用来阐明分子结构的最有力的工具。它被用来识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱是必不可少的。该奖项由化学共享仪器计划、材料研究仪器计划和界面、运输和热力学过程计划支持，将帮助克拉克大学化学系获得一台大口径核磁共振光谱仪。拟议的仪器不仅将为该部服务，而且将在伍斯特联盟的支持下由该区域的一些科学家共享。此次收购将加强伍斯特联盟的研究领域，包括：1)聚合物体系的动力学和结构2)G蛋白质-配体相互作用的核磁共振研究3)固定化对分光光度和荧光试剂固有选择性的影响4)用核磁共振和重量法研究分子筛分子筛中的晶内扩散5)抗体结合部位的核磁共振研究

Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to the chemist for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solutions. Access to state-of-the-art NMR spectrometry is essential to chemists who are carrying out frontier research. This award, supported by the Chemistry Shared Instrumentation Program, the Instrumentation for Materials Research Program and the Interfacial, Transport, & Thermodynamic Processes Program will help the Department of Chemistry at Clark University to acquire a wide bore NMR spectrometer. The proposed instrument will serve not only the Department but will be shared by a number of scientists in the region through the aegis of the Worcester Consortium. The areas of research in the Worcester Consortium that will be enhanced by the acquisition include: 1) Dynamics and Structure in Polymeric Systems 2) NMR Studies of G Protein-Ligand Interactions 3) Effect of Immobolization of the Inherent Selectivity of Spectrophotometric and Spectrofluorometric Reagents 4) Study of the Intracrystalline Diffusion in Molecular Sieve Zeolites by NMR and Gravimetric Methods 5) NMR Studies on Antibody Binding Sites