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Cellular Characterization of the Maize Auxin Receptor

玉米生长素受体的细胞表征

基本信息

批准号：
8915327
负责人：
Alan Jones
金额：
$ 23.7万
依托单位：
University of North Carolina at Chapel Hill
依托单位国家：
美国
项目类别：
Continuing Grant
财政年份：
1990
资助国家：
美国
起止时间：
1990-02-01 至 1993-07-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=8915327&HistoricalAwards=false
关键词：
Cellular Characterization Maize Auxin Receptor

项目摘要

Growth, a fundamental process of all cells, is mediated by a specific interaction between a hormone and its receptor at a specific cellular address. In plants, growth is mediated by the specific interaction of the growth-promoting hormone, auxin, and the auxin receptor, however, there is now substantial evidence, although it is still indirect, that the auxin receptor and its gene has been identified. There are several unique features of this receptor, the most important is that most of it is found sequestered in a cellular compartment. No other growth hormone receptor shares this properties and it raises the question of the mechanism by which this receptor perceives hormone on the outside of the cell and mediates growth. The following questions are addressed in this proposal: Where in the tissue and cell is the auxin receptor located and does this location change during cell development? Where is the cellular site of auxin perception by the auxin receptor and is this different than the location of the bulk of the receptor population? Does the presence of the receptor correlate with auxin-induced growth capacity? In many instances, growth in plants is limited by the abundance of the auxin receptor. An understanding of how this limitation is regulated in the plant will lend insight into how mankind can manipulate plant growth and crop yields.

生长是所有细胞的一个基本过程，它是由激素与其受体在特定细胞地址上的特定相互作用所介导的。在植物中，生长是由促生长激素、生长素和生长素受体的特定相互作用介导的，然而，现在有大量的证据表明，尽管仍然是间接的，生长素受体及其基因已经被确定。这种受体有几个独特的特征，最重要的是它的大部分被发现隔离在一个细胞隔间里。没有其他生长激素受体具有这种特性，这就提出了这个受体在细胞外感知激素并调节生长的机制的问题。该提案解决了以下问题：生长素受体在组织和细胞中的位置以及在细胞发育过程中该位置是否发生变化？生长素受体感知生长素的细胞位置在哪里？这与大部分受体群体的位置不同吗？受体的存在是否与生长素诱导的生长能力相关？在许多情况下，植物的生长受到生长素受体丰度的限制。了解这种限制在植物中是如何调节的，将有助于了解人类如何操纵植物生长和作物产量。