Purchase and Maintenance of a 500 MHz NMR Spectrometer (Chemistry)

500 MHz NMR 波谱仪（化学）的购买和维护

• 批准号: 8722596
• 负责人: Louis Pignolet
• 金额: $ 23.2万
• 依托单位: University of Minnesota-Twin Cities
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-06-15 至 1989-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8722596&HistoricalAwards=false
• 关键词: Purchase; Maintenance; 500; MHz; NMR

Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to the chemist for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectroscopy is essential to chemists who are carrying out frontier research. This award, joint-funded by the Chemistry Shared Instrumentation Program and the Biological Instrumentation Program, will help the Chemistry Department of the University of Minnesota to acquire a high-field NMR spectrometer. The areas of research that will be enhanced by the acquisition include: 1) Study of bonding and reaction mechanisms in Organic chemistry 2) Complete structural characterization of complex carbohydrates by the reductive cleavage method 3) Natural product synthesis and NMR 4) Biosynthesis of natural products 5) Mechanisms of biosynthetic formation of deoxy sugars 6) Structure and mechanism of non-heme iron containing proteins using NMR spectroscopy.

核磁共振波谱是化学家用来阐明分子结构的最有力的工具。它被用来识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振波谱是必不可少的。该奖项由化学共享仪器计划和生物仪器计划联合资助，将帮助明尼苏达大学化学系获得一台高场核磁共振光谱仪。此次收购将加强的研究领域包括：1)研究有机化合物的成键和反应机理化学2)用还原裂解法完成复杂碳水化合物的结构表征3)天然产物合成和核磁共振4天然产物的生物合成5)脱氧糖的生物合成形成机理6)用核磁共振波谱研究非血红素含铁蛋白质的结构和机理。