Organic Bioelectronics: Solving Key Barriers to Precision Neuromodulation

有机生物电子学：解决精准神经调节的关键障碍

• 批准号: DP230102705
• 负责人: Dr Matthew Griffith
• 金额: $ 32.72万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2023
• 资助国家: 澳大利亚
• 起止时间: 2023-02-01 至 2026-01-31
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP230102705
• 关键词: Organic; Bioelectronics; Solving; Key; Barriers

This project aims to combine the principles of molecular electronics and neurobiology to create organic conductors with enhanced biocompatibility that enable optical neuromodulation. This project expects to generate new knowledge regarding the properties of materials that promote connectivity with neurons and the ability of new microscopy tools to visualise this bio-interface. The expected outcome of this project includes new high performing materials, measurement tools and fabrication approaches to overcome the key challenges to precision neuromodulation. A significant benefit of the new materials is their printability, providing the opportunity to establish a sovereign capability to manufacture low-cost bioelectronic systems in Australia.

该项目旨在将分子电子学和神经生物学的原理联合收割机，以创建具有增强生物相容性的有机导体，从而实现光学神经调节。该项目预计将产生有关促进与神经元连接的材料特性的新知识，以及新的显微镜工具可视化这种生物界面的能力。该项目的预期成果包括新的高性能材料、测量工具和制造方法，以克服精密神经调节的关键挑战。新材料的一个重要好处是它们的可印刷性，为在澳大利亚建立低成本生物电子系统的主权能力提供了机会。