Purchase of a High Field FT-NMR

核磁共振波谱是化学家用来阐明分子结构的最有力的工具。它被用来识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于正在进行前沿研究和教育学生成为下一代化学家的化学家来说，接触最先进的核磁共振波谱是必不可少的。高露洁大学化学系将利用化学共享仪器计划的这一RUI奖来帮助获得一台高场核磁共振光谱仪。这项收购将增强系培养本科生的能力，并将加强以下领域的化学研究：1)金属-碳键形成的热力学研究2)有机锡配合物的结构表征和动力学3)氚代小环烃的气相动力学4)棘球菌素合成中间体的立体和区域化学表征5)哺乳动物碳酸酐酶的动力学研究6)铑-多齿胺络合物的立体化学表征。

Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to the chemist for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules,and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectroscopy is essential to chemists who are carrying out frontier research and educating students who will become the next generation of chemists. The Department of Chemistry at Colgate University will use this RUI award from the Chemistry Shared Instrumentation Program to help acquire a high-field NMR spectrometer. The acquisition will enhance the ability of the Department to educate undergraduate students and will enhance chemical research in the following areas: 1) Thermodynamic studies of metal-carbon bond formation in rhodium porphyrin compounds 2) Structural characterization and dynamics of organotin complexes 3) Gas phase kinetics of deuterated small cyclic hydrocarbons 4) Stereo- and regiochemical characterization of intermediates in the synthesis of echinosporin 5) Kinetic studies on mammalian carbonic anhydrases 6) Stereochemical characterization of rhodium-multidentate amine complexes.