Computing Resource for Sequence Analysis

请求为一个整个校园的计算设施提供支助， 将用于提供对序列分析程序的访问， 序列数据库。 该设施将支持20多个 资助的，正在进行的，在学院的基础科学研究项目 科学，医学和农业。 这些种类繁多的 项目需要在计算机上存储序列，分析 通过序列比对和模式发现方法， 从数据库中检索序列， 蛋白质或RNA的二级结构。 虽然简单类型的序列分析是常规的， 在实验室微型计算机上进行， 亚利桑那大学没有准备好进入更复杂的 程序或序列数据库的类型。 最可行的 这个问题的解决方案是提供一个共享的计算 设施配备了一套软件包，如 威斯康星州的DNA序列分析计划，这将提供最 所需的程序和数据库。 拟议设施 将通过直接电缆或电话提供计算机接入 调制解调器，并将联网到现有的计算系统。

Support is requested for a campus-wide computing facility which will be used to provide access to sequence analysis programs and sequence databases. This facility will support more than 20 funded, on-going, basic science research projects in the Colleges of Science, Medicine and Agriculture. A large variety of these projects require storage of sequences on the computer, analysis of sequences by sequence alignment and pattern finding methods, retrieval of sequences from databases, and prediction of secondary structure of proteins or RNA from their sequence. Although simple types of sequences analysis are routinely performed on laboratory microcomputers, laboratories at the University of Arizona do not have ready access to more complex types of programs or sequences databases. The most feasible solution to this problem is to provide a shared computing facility equipped with a set of software packages such as the Wisconsin DNA sequence analysis programs, which will provide most of the required programs and databases. The proposed facility will provide computer access by direct cable or a telephone modem, and will be net worked to an existing computing system.