The Influence of Juvenile Hormone on the Reproduction

保幼激素对生殖的影响

• 批准号: 8821339
• 负责人: John Ringo
• 金额: $ 0.8万
• 依托单位: University of Maine
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-05-15 至 1991-10-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8821339&HistoricalAwards=false
• 关键词: Influence; Juvenile; Hormone; Reproduction

Dr. Ringo has an excellent model system to determine how genetic changes affect behavior by the endocrine system. The apterous locus in Drosophila is crucial for the survival of embryos and young, and for the normal development of wings and specific endocrine glands that are involved in the production and secretion of juvenile hormone. Juvenile hormone is a major growth regulator in insects as well as being required for normal oogenesis and the development of reproductive behavior. Using a multidisciplinary approach, Dr. Ringo will genetically dissect the endocrine basis of reproduction in Drosophila. Using specific mutations of the apterous gene, he can define precisely the extent and timing of the behavioral defects, and determine the exact relationship between these defects and the level of juvenile hormone. This research not only open doors at elucidating the molecular basis of hormonally controlled behavior patterns, but it could lead to noninvasive means of insect pest control. This is very important especially given the recent controversy surrounding chemical spraying for control of insects, specifically flys, in populated environments.

林戈博士有一个很好的模型系统来确定基因 内分泌系统的变化影响行为。 无翅的 基因座对胚胎的存活至关重要， 年轻，翅膀和特定的正常发育 内分泌腺参与生产， 保幼激素的分泌。 保幼激素是一种主要的 生长调节剂在昆虫以及所需的正常 卵子发生和生殖行为的发展。 使用 多学科的方法，林戈博士将基因解剖 果蝇生殖的内分泌基础 使用 无翅基因的特定突变，他可以精确地定义 行为缺陷的程度和时间，并确定 这些缺陷和水平之间的确切关系 保幼激素 这项研究不仅打开了大门， 阐明生殖控制行为的分子基础 模式，但它可能会导致非侵入性的手段， 控制 这一点非常重要，特别是考虑到最近 围绕喷洒化学药剂控制昆虫的争议， 特别是苍蝇。