A National Neural Circuitry Database (NCDB): Development ofa Shared Information Resource for Basic and Clinical Neuroscience

这不是一个研究项目，而是一个试图在专家之间就科学界对国家神经回路数据库（NCDB）的要求和实施达成共识的项目。本项目的主要目标是：(1)对建立国家开发银行的要求和适当性提出立场；(2)确定构成国家信息数据库的数据范围和要素；(3)定义数据的精确表示格式。这一目标可能允许将空间和解剖数据与文本和表格字母数字数据联系起来，使其能够在图形和字母数字数据和信息之间轻松移动；(4)描述一个原型或可选的计算机系统，无论是目前存在的，还是正在开发中，它可以用于数据存储，并将允许各种研究人员之间的最佳数据通信和共享；(5)描述1.2个现有的国家数据库系统，说明数据存储、表示、检索和共享的各种配置。在此描述中包括这些系统可以为成功建立数据库提供的任何记录在案的经验和潜在的缺陷（如果可用）；(6)概述NCDB如何在结构上进行最佳组织，以便能够有效地建立和最大限度地组织供神经科学研究界临床研究者和教育工作者使用。这应包括对任务和目标进行理想的排序，并对需要进行财政和时间估计；(7)根据实现这些目标的经验教训，为NIMH、NIDA和NSF就建立nncdb的项目发展的未来方向和政策提出建议。

This is not a research project but one which attempts to arrive at a consensus among experts regarding the requirements of the scientific community for, and implementation of a National Neural Circuitry Database (NCDB). The major objectives of this project are to: (1) Formulate a position on the requirements for and appropriateness of establishing a NCDB; (2) Define the scope and elements of data that would constitute the NCDB; (3) Define the precise format for representation of data. This goal may allow for the linkage of spatial and anatomical data with text and tabular alphanumeric data in a way that makes it possible to move easily between graphical and alphanumeric data and information; (4) Describe a prototypic or optional computer system that either currently exists, or is under development, which can be used for data storage and which will allow for optimal data communications and sharing among various investigators; (5) Describe 1.2 currently existing national database systems that illustrate various configurations for data storage, representation, retrieval and sharing. Within this description include any documented experiences that these systems can provide for the successful establishment of the database and potential pitfalls, if available; (6) Outline how the NCDB can be best organized in structure so that it can be efficiently established and maximally organized for use by the neuroscience research community clinical investigators, and educators. This should include an ideal ordering of tasks and goals with both fiscal and temporal estimates of need; and (7) Based on what is learned from fulfilling these objectives, make recommendations on the future directions and policy in program development for the NIMH, NIDA and NSF with respect to establishment of a NCDB.