Membrane Fusion and Chemotropic Approaches to Peripheral Nerve Regeneration (REU Supplement)

周围神经再生的膜融合和趋化方法（REU 补充）

• 批准号: 8915178
• 负责人: Jeffrey Hubbell
• 金额: $ 59.07万
• 依托单位: University of Texas at Austin
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-09-01 至 1993-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8915178&HistoricalAwards=false
• 关键词: Membrane; Fusion; Chemotropic; Approaches; Peripheral

This project is a collaboration between a chemical engineer and a physiologist, to develop new chemical systems to encourage nerve regeneration. This involves fundamental research in determining what substances cause nerve growth, and in building synthetic polymer substrates capable of supplying such substances when implanted into the human body. Similar basic research will focus on the problem of fusing cell membranes, so as to reconnect nerve systems. If this work is successful, it would have major medical benefits; furthermore, it might possibly be a step towards future work more relevant to the central nervous system, a topic which is difficult to work with but could involve very large long-term benefits to humanity.

该项目是化学工程师和生理学家之间的合作，旨在开发新的化学系统来促进神经再生。 这涉及基础研究，以确定哪些物质会导致神经生长，以及构建在植入人体后能够提供此类物质的合成聚合物基质。 类似的基础研究将集中在融合细胞膜的问题上，从而重新连接神经系统。 如果这项工作成功，将会带来重大的医疗效益；此外，这可能是朝着与中枢神经系统更相关的未来工作迈出的一步，这个话题很难处理，但可能会给人类带来非常大的长期利益。