Studies of Fiber-Optic-Based Immunosensors

基于光纤的免疫传感器的研究

• 批准号: 8921517
• 负责人: Frank Bright
• 金额: $ 22.3万
• 依托单位: SUNY at Buffalo
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-04-01 至 1993-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8921517&HistoricalAwards=false
• 关键词: Studies; Fiber; Optic; Based; Immunosensors

This grant is in the general area of analytical and surface chemistry and in the subfield of fiber optic biosensors. Professor Bright will pursue the development of an immunosensor based on the immobilization of fluorescently labeled antibody fragments on fiber optic surfaces. This research will use time-resolved fluorescence spectroscopy to optimize the development of the surface immobilization chemistry. The long term goal of this research will be to develop fiber optic immunosensor schemes that may be applicable to in vivo analyses. This is not a goal of the present research. Success in this research would provide a means of quantifying both haptens and antibodies in vivo.

这项补助金是在一般领域的分析和表面 化学和光纤生物传感器的子领域。 布莱特教授将致力于免疫传感器的开发 基于荧光标记抗体的固定 光纤表面的碎片。 这项研究将使用时间分辨荧光光谱法 以优化表面固定化的发展 化学. 这项研究的长期目标是 开发可能适用的光纤免疫传感器方案 到体内分析。 这不是当前的目标 research. 这项研究的成功将提供一种手段， 在体内定量半抗原和抗体。