Studies of Highly Reactive Molecules and Intermediates

高反应性分子及中间体的研究

• 批准号: 8921744
• 负责人: Thomas Hoye
• 金额: $ 79.5万
• 依托单位: University of Minnesota-Twin Cities
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-01-15 至 1995-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8921744&HistoricalAwards=false
• 关键词: Studies; Highly; Reactive; Molecules; Intermediates

The Organic Synthesis Program will support the continuation of the research of Dr. Paul G. Gassman. Dr. Gassman will continue his productive studies on highly strained systems and initiate work on the synthesis of ligands for transition metals. These will be used to change the apparent oxidation state of the metal. This increased control of the oxidation state will facilitate the synthesis of the increasingly complex materials needed by our economy. Studies in the area of organometallic chemistry will be centered on the use of X-ray photoelectron spectroscopy (XPS) to understand the electronic influence of ligands on complexed transition metals. New ligands will be prepared which are either more electron withdrawing or electron donating than currently available ligands. It is planned to prepare and study the properties of complexes which can serve as either oxidants or reductants as a function of the attached ligands. Work will continue on studies of trans-bicycloın.1.0!alkanes, strained paracyclophanes, and electron transfer from strained rings. New synthetic applications of electrochemical reductions will be explored. Improved excited state oxidants will be sought in an approach to the development of synthetically useful procedures for anti-Markovnikov addition of nucleophiles to simple olefins. Studies of radicals, anion radicals, cation radicals and cations will be carried out.

有机合成计划将继续支持 Paul G博士的研究。加斯曼 Gassman博士将继续 他对高应变系统的富有成效的研究， 过渡金属配体的合成。 这些 将被用来改变表观氧化态的 金属. 这种对氧化态的增强控制将 促进日益复杂的材料的合成， 我们的经济需要。 在有机金属化学领域的研究将是 以X射线光电子能谱（XPS）的使用为中心， 了解配体对络合物的电子影响， 过渡金属 将制备新的配体， 吸电子或给电子量大于 目前可用的配体。 计划准备和 研究复合物的性质， 氧化剂或还原剂作为连接的配体的函数。 反式双环1.0的研究工作将继续进行！烷烃， 应变paracyclophanes，和电子转移从应变 环. 电化学合成新应用 将探讨削减。 改进的激发态氧化剂 将寻求一种方法， 反马氏加成合成方法 亲核试剂转化为简单的烯烃。 自由基、阴离子的研究 自由基、阳离子自由基和阳离子将被进行。