US-UK Cooperative Research: Strategies For Assessment and Control of Parasitological Water Quality

美英合作研究：寄生虫水质评估和控制策略

• 批准号: 8922664
• 负责人: Joan Rose
• 金额: $ 1.91万
• 依托单位: University of South Florida
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-07-15 至 1992-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8922664&HistoricalAwards=false
• 关键词: US; UK; Cooperative; Research; Strategies

This award will support collaborative research in environmental engineering between Dr. Joan Rose, University of South Florida and Dr. Jeni Colbourne, Thames Water Authority, New River Head Laboratories, London, England. The objectives of the project are to develop strategies for assessing the occurence and concentrations of enteric protozoa in potable water supplies, and then to apply risk assessment models for the development of control approaches for water engineers in the US and UK. Recently, two large waterborne outbreaks of Cryptosporidium have occured in the US and the UK in water systems which treat the water by coagulation, filtration and disinfection in the absence of any violation of standards. The proposed research will evaluate protozoan contamination (Cryptosporidium in particular) of the Thames Water Authority's catchment basin, comparing gene probe technology to immunofluorescent techniques. Specifically, the investigators will: 1) compare gene probes for rapid detection of cysts to the immunofluorescent techniques currently used for water samples collected during a survey of catchment basin, 2) evaluate the capability of the various treatments to remove Cryptosporidium cysts and Giardia cysts, and 3) apply a risk assessment model based on cyst concentrations in source waters and potential treatment to define the health impact. The results of this research will promote communication on a common problem facing the water industry, assist in developing and standardizing procedures for assessing environmental protozoan contamination and define appropriate treatment approaches which will help eliminate waterborne Cryptosporidisis. The project will benefir from the complementary expertise of the two, investigators: Dr. Rose has had significant involvement with surveys for Cryptosporidium and Giardia in water, as well as with the development of immunoflourescent techniques. Dr. Colbourne has developed standardized procedures for parasite recovery and detection.

该奖项将支持环境领域的合作研究 琼·罗斯博士，南佛罗里达大学 和Jeni Colbourne博士，泰晤士水务局，新河头 实验室，伦敦，英国。 该项目的目标 是制定评估发生率的策略， 饮用水供应中肠道原生动物的浓度， 然后应用风险评估模型， 美国和英国水工程师的控制方法。 最近，两次大规模的水传播隐孢子虫爆发， 发生在美国和英国的水系统， 水通过混凝，过滤和消毒的情况下， 任何违反标准的行为 拟议的研究将 评估原生动物污染（特别是隐孢子虫） 泰晤士水务局的集水盆地，比较基因 探针技术到免疫荧光技术。 具体地说， 研究人员将：1）比较基因探针， 免疫荧光技术检测囊肿 用于集水区调查期间收集的水样 盆地，2）评估各种处理的能力， 去除隐孢子虫包囊和贾第鞭毛虫包囊，以及3） 基于源中包囊浓度的风险评估模型 沃茨和潜在的治疗，以确定健康影响。 本研究的结果将促进在一个 水务行业面临的共同问题，协助发展 和标准化评估环境 原生动物污染，并确定适当的治疗方法 有助于消除水传播的方法 隐孢子虫病 该项目将受益于互补的 两人的专业知识，研究人员：罗斯博士有显着的 参与调查隐孢子虫和贾第虫， 水，以及免疫荧光的发展 技术. 科尔伯恩医生制定了标准化的程序 用于寄生虫回收和检测。