PYI: Ontogeny and Phylogeny of the Tetrapod Skeleton

PYI：四足动物骨骼的个体发育和系统发育

• 批准号: 8958092
• 负责人: Timothy Rowe
• 金额: $ 27.45万
• 依托单位: University of Texas at Austin
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-09-01 至 1995-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8958092&HistoricalAwards=false
• 关键词: PYI; Ontogeny; Phylogeny; Tetrapod; Skeleton

Dr. Timothy Rowe of the University of Texas at Austin will devote his time during the five years of this Presidential Young Investigator Award to using phylogenetic systematics to explore the evolution of mammalian ontogeny. This work logically follows from previous research, which analyzed skeletal evolution in the major groups of Mammalia and the closest extinct relatives within Synapsida (early reptilian forms ancestral to true mammals). Nearly 1,000 historic transformations of the skeleton were summarized as a result. It is now possible to refer to this information while examining skeletal development in living mammals. Cladistic methods will be used to analyze skeletal development in selected mammalian and tetrapod species, phylogenetic transformations and sequences of transformations that recapitulate in ontogeny, and disruptions or deletions in transformation sequences. To accomplish these goals, it will be necessary to acquire developmental information from cleared and stained embryos of extant mammal species; serial sections, and images (from nuclear magnetic resonance techniques, from rare or endangered species) will also be processed and incorporated into the data set. The research described above has exceptional potential for generating new data and for syntheses with previous observations to solve long-standing problems in evolutionary biology. In addition, it highlights the importance of systematic biology in supplying a unifying theme to threads from the disparate fields of molecular and developmental biology, comparative anatomy, and paleontology.

德克萨斯大学奥斯汀分校的蒂莫西·罗博士将致力于 在这五年的总统任期内， 研究者奖：使用系统发育分类学来探索 哺乳动物个体发育的进化 这项工作逻辑上遵循 从以前的研究，其中分析了骨骼的演变， 哺乳动物的主要群体和最近灭绝的亲属内 Synapsida（早期爬行动物的形式祖先真正的哺乳动物）。 近1,000个历史性的骨架变化， 总结为结果。 现在可以参考这个 信息，同时检查骨骼发育在生活中 哺乳动物 分支系统学方法将被用来分析骨骼发育 在选定的哺乳动物和四足动物物种中， 变换和变换序列， 在个体发育中重演， 变换序列 为了实现这些目标， 需要从已清除的和 现存哺乳动物物种的染色胚胎;连续切片，以及 图像（来自核磁共振技术，来自罕见或 濒危物种）也将被处理并纳入 数据集。 上述研究具有特殊的潜力， 生成新数据并与以前的观测结果进行综合 来解决进化生物学中长期存在的问题。 在 此外，它还强调了系统生物学在 为来自不同领域的线程提供统一的主题 分子和发育生物学，比较解剖学， 古生物学