Intrinsic Reactivity from Competitive Ion-Molecule Reactions in the Gas-Phase

这项来自有机动力学项目的资助支持了这项工作 约瑟夫·J·格拉博夫斯基博士在哈佛大学。 结果 这项调查将提供新的见解， 化学过程的基本细节， 反应发生。 格拉博夫斯基博士将采用流动的余辉和选定的 离子流管技术用于检查、探测和定义 气相、有机、离子-分子反应的机理。 将采用竞争性反应，以使准确的产品 比率将提供有关替代方案的直接信息 在没有溶剂效应的情况下的反应通道。 两 正离子和负离子系统将进行研究， 研究将集中在这些反应对的比较上 作为消除取代，竞争性H原子转移，和 在同一个不同的杂化碳中心反应 分子。

This grant from the Organic Dynamics Program supports the work of Dr. Joseph J. Grabowski at Harvard University. The results of this investigation will provide new insights into the fundamental details of the processes by which chemical reactions take place. Dr. Grabowski will employ the Flowing Afterglow and Selected Ion Flow Tube techniques to examine, probe, and define mechanisms of gas-phase, organic, ion-molecule reactions. Competitive reactions will be employed so that accurate product ratios will provide direct information about the alternative reaction channels in the absence of solvent effects. Both positive-ion and negative-ion systems will be studied, and the investigation will focus on comparisons of such reaction pairs as elimination-substitution, competitive H-atom transfers, and reactions at differently hybridized carbon centers in the same molecule.