RPG/ROW: Evolution of the Mammalian Y Chromosome

RPG/ROW：哺乳动物 Y 染色体的进化

• 批准号: 9009806
• 负责人: Priscilla Tucker
• 金额: $ 1.8万
• 依托单位: Regents of the University of Michigan - Ann Arbor
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-08-01 至 1991-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9009806&HistoricalAwards=false
• 关键词: RPG; ROW; Evolution; Mammalian; Chromosome

In this Research Opportunities for Women/ Research Planning Grant, Dr. Priscilla Tucker, at the University of Michigan, proposes a preliminary evaluation of DNA sequence data from the mammalian Y-chromosome for its use in systematic studies. Y- chromosome genes are of interest because they are inherited only through male lineages and, thus, will provide a useful contrast to mitochondrial genes which are inherited strictly through female lineages. Specifically, Dr. Tucker will use DNA probes for a sequence called pY8/B to survey species in the rodent tribe Peromyscini. The distribution of the pY8/b region will be studied in context of the evolutionary history of the group. The exact nucleotide sequences for the pY8/B sequence will also be determined for several species, and the value of the sequence data for inferring the evolutionary history of the group determined. The research will make an important contribution to understanding the origin of biodiversity in mammalian species.

在本研究中，妇女的研究机会/研究规划 格兰特，密歇根大学的普里西拉·塔克博士， 提出了一个初步评估的DNA序列数据从 哺乳动物Y染色体，用于系统研究。是的，是的 染色体基因是感兴趣的，因为它们只遗传 通过男性血统，因此，将提供一个有用的对比， 线粒体基因严格通过 女性血统具体来说，塔克博士将使用DNA探针来 一个叫做pY 8/B的序列用来调查啮齿类的物种 Peromyscini。pY 8/B区的分布如下： 在这个群体进化史的背景下进行研究。的 pY 8/B序列的确切核苷酸序列也将被 确定了几个物种，和序列的值 用于推断该群体进化历史的数据 测定这项研究将为 了解哺乳动物物种生物多样性的起源。