CAA/ROW: Molecular Evolution of Histone Genes

CAA/ROW：组蛋白基因的分子进化

• 批准号: 9009938
• 负责人: Linda Strausbaugh
• 金额: $ 5.61万
• 依托单位: University of Connecticut
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-09-15 至 1992-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9009938&HistoricalAwards=false
• 关键词: CAA; ROW; Molecular; Evolution; Histone

In this ROW/CAA (Research Opportunities for Women/ Career Advancement Award) project, Dr. Linda Strausbaugh at the University of Connecticut proposes to study the evolution of the histone gene family in the Drosophila willistoni species complex. The histones are a class of proteins universal in living organisms which, because of their functional importance in chromosomes, have been highly conserved by evolution. Strausbaugh has found evidence of histone gene variation among closely related species of the D. willistoni complex and proposes a series of experiments to test theories about the evolution of histone genes. Dr. Strausbaugh is a molecular geneticist attempting to carry her research into the realm of evolutionary biology. Under the ROW/CAA program she will continue her work initiated while on sabbatical leave at Yale University during the 1989-90 academic year; specifically, she will "re-tool" her laboratory for studies in molecular evolution, initiate several new projects and complete the projects initiated at Yale.

在这个ROW/CAA（妇女/职业研究机会） 进步奖）项目，琳达施特劳斯博士在 康涅狄格大学提议研究 Drosophila willistoni物种复合体中的组蛋白基因家族。 组蛋白是一类普遍存在于生命活动中的蛋白质 生物体，由于其功能的重要性， 在进化过程中一直高度保守。Strausbaugh 发现了组蛋白基因变异的证据， 近缘种D. willistoni复杂，并提出了一个 一系列的实验来测试关于进化的理论， 组蛋白基因施特劳斯博士是一位分子遗传学家 试图将她的研究带入进化论领域 生物学在ROW/CAA计划下，她将继续她的工作 在耶鲁大学休假期间发起， 1989-90学年;具体来说，她将“重新装备”她的 分子进化研究实验室，发起了几个 新的项目，并完成在耶鲁发起的项目。