Purchase of X-Ray Diffraction System

单晶X射线晶体学是最强大的 测定固体结构的分析方法。 在 合成无机、有机、生物无机和有机金属 单晶X射线衍射是一种非常宝贵的 表征分子结构的工具。 的信息 从分子组成的知识中获得， 结构有助于开发潜在的通用的新反应， 对催化或合成感兴趣。 化学共享仪器计划（Chemistry Shared Instruments Program） 将帮助密苏里州大学的化学系 哥伦比亚公司购买了新的X射线衍射仪系统， 现有衍射仪的升级。 的区域中底 此次收购将加强化学研究， 如下： L. ~（105）Rh和~（199）Au的双功能螯合物 放射药物 2. 后过渡金属铀-氧代和铀-亚胺配合物 3. 亚硝胺化学与致癌作用 4. 新臭氧化学 5. 分子内4+3环加成与分子裂缝 6. 官能化表面活性剂和环糊精在制备纳米颗粒中的应用 化学分析 7. 肽类真菌毒素和铁载体的结构研究 8. 准芳香金属环的反应性 9. 电子密度分布的直接测量 晶体

Single crystal X-ray crystallography is the most powerful analytical method for structure determination of solids. In synthetic inorganic, organic, bioinorganic and organometallic chemistry, single crystal X-ray diffraction is an invaluable tool to characterize molecular structure. The information gained from the knowledge of the molecular composition and structure helps to develop new reactions of potentially general interest in catalysis or synthesis. This award from the Chemistry Shared Instrumentation Program will help the Department of Chemistry at University of Missouri Columbia acquire a new X-ray diffractometer system and purchase an upgrade of the existing diffractometer. Among the areas of chemical research that will be enhanced by the acquisition are the following: l. Bifunctional Chelates of 105 Rh and 199 Au as Potential Radiopharmaceuticals 2. Late Transition Metal u-Oxo and u-Imido Complexes 3. Nitrosamine Chemistry and Carcinogenesis 4. New Ozonide Chemistry 5. Intramolecular 4+3 Cycloadditions and Molecular Clefts 6. Use of Functionalized Surfactants and Cyclodextrin in Chemical Analysis 7. Structural Studies of Peptide Mycotoxins and Siderophores 8. Reactivity of Quasi-Aromatic Metal Rings 9. Direct Measurement of Electron Density Distributions in Crystals