Purchase of X-Ray Diffraction System

购买X射线衍射系统

• 批准号: 9011804
• 负责人: Elmer Schlemper
• 金额: $ 17.01万
• 依托单位: University of Missouri-Columbia
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-07-01 至 1993-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9011804&HistoricalAwards=false
• 关键词: Purchase; Ray; Diffraction; System

Single crystal X-ray crystallography is the most powerful analytical method for structure determination of solids. In synthetic inorganic, organic, bioinorganic and organometallic chemistry, single crystal X-ray diffraction is an invaluable tool to characterize molecular structure. The information gained from the knowledge of the molecular composition and structure helps to develop new reactions of potentially general interest in catalysis or synthesis. This award from the Chemistry Shared Instrumentation Program will help the Department of Chemistry at University of Missouri Columbia acquire a new X-ray diffractometer system and purchase an upgrade of the existing diffractometer. Among the areas of chemical research that will be enhanced by the acquisition are the following: l. Bifunctional Chelates of 105 Rh and 199 Au as Potential Radiopharmaceuticals 2. Late Transition Metal u-Oxo and u-Imido Complexes 3. Nitrosamine Chemistry and Carcinogenesis 4. New Ozonide Chemistry 5. Intramolecular 4+3 Cycloadditions and Molecular Clefts 6. Use of Functionalized Surfactants and Cyclodextrin in Chemical Analysis 7. Structural Studies of Peptide Mycotoxins and Siderophores 8. Reactivity of Quasi-Aromatic Metal Rings 9. Direct Measurement of Electron Density Distributions in Crystals

单晶X射线结晶学是测定固体结构的最有力的分析方法。在合成无机化学、有机化学、生物无机化学和有机金属化学中，单晶X射线衍射是表征分子结构的宝贵工具。从分子组成和结构知识中获得的信息有助于开发在催化或合成方面具有潜在普遍兴趣的新反应。化学共享仪器项目的这一奖项将帮助密苏里哥伦比亚大学化学系获得新的X射线衍射仪系统，并购买现有衍射仪的升级。此次收购将加强的化学研究领域如下：L。潜在的105Rh和199Au的双功能络合物放射性药物2.后过渡金属u-氧和u-亚胺配合物3.亚硝胺化学与致癌4.新臭氧化学5.分子内4+3环加成反应和分子裂解6.官能化表面活性剂和环糊精在分子中的应用化学分析7.多肽、霉菌毒素和铁载体的结构研究8.类芳香族金属环的反应性9.晶体中电子密度分布的直接测量