Motility and Chemotaxis in Eosinophilic Leukocytes

嗜酸性白细胞的运动性和趋化性

• 批准号: 9011852
• 负责人: Susan Gilbert
• 金额: $ 6万
• 依托单位: University of Massachusetts Medical School
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-09-01 至 1992-02-29
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9011852&HistoricalAwards=false
• 关键词: Motility; Chemotaxis; Eosinophilic; Leukocytes

This is a Career Advancement Award to support Dr. Gilbert's work as a guest investigator in the laboratory of Dr. Frederick Fay at the University of Massachusetts Medical Center. The goal of the project is to define the respective roles of microtubules and actin microfilaments in cell polarization and chemotaxis, using eosinophilic leukocytes from newts as a model system. Dr. Gilbert will be combining her background and expertise in the biophysics of muscle motility with the expertise of Dr. Fay's laboratory, which includes fluorescence microscopy and microinjection, to develop a new line of research which is anticipated to significantly enhance her career.

这是一个职业发展奖，以支持Gilbert博士作为马萨诸塞大学医学中心Frederick Fay博士实验室的客座研究员所做的工作。该项目的目标是利用蝾螈嗜酸性白细胞作为模型系统，确定微管和肌动蛋白微丝在细胞极化和趋化中的各自作用。Gilbert博士将把她在肌肉运动生物物理学方面的背景和专业知识与Fay博士实验室的专业知识（包括荧光显微镜和显微注射）结合起来，开发一条新的研究路线，预计将大大提高她的职业生涯。