U.S.-Japan Joint Seminar: Biology of the Epidermis (July, 21-25, 1991 Sapporo, Japan)

该奖项支持六名美国科学家参加1991年7月21日至25日在日本札幌举行的“表皮生物学”美日联合研讨会。协办方是斯坦福大学医学院皮肤学系Joseph McGuire教授和日本札幌北海道大学医学院皮肤学系Akira Ohkawara教授。研讨会将讨论的具体主题包括(1)角质层和细胞外脂质；(2)表皮结构蛋白；(3)调节细胞增殖和分化、维生素D3、生长因子和细胞因子；(4)角质形成细胞癌基因的表达。这将是1976年以来关于这个问题的第五次讨论会。这些研讨会在促进和促进美国和日本皮肤科医生和皮肤研究人员之间的互动方面发挥了重要作用。由于自1985年上次研讨会以来已经了解了许多关于表皮的信息，因此提议的研讨会特别及时。表皮覆盖整个人体，保护内脏器官，维持人体稳态。为了保护和维持适当的体内平衡，表皮具有高度组织化的特征和功能。已经进行了大量的研究，试图理解这些，集中在定义表皮的形态和生化特性。该领域正在迅速扩大，特别是在分子生物学和细胞生长和分化的调节领域。目前，皮肤科学领域正在做出重大贡献，这将最终导致解决各种皮肤病的发病机制。由于研讨会将讨论最近取得重大进展的主题，因此会议应使美国和日本的研究界了解最新情况，并促进未来的合作项目。

This award supports the participation of six US scientists in a joint US-Japan seminar on "Biology of the Epidermis," July 21-25, 1991 in Sapporo, Japan. The co-organizers are Professor Joseph McGuire, Department of Dermatology, Stanford University School of Medicine, and Professor Akira Ohkawara, Department of Dermatology, Hokkaido University School of Medicine, Sapporo, Japan. Specific topics to be discussed at the seminar include (1) stratum corneum and extracellular lipids; (2) structural proteins of the epidermis; (3) regulation of proliferation and differentiation, vitamin D3, growth factors and cytokines; and (4) expression of oncogenes by keratinocytes. This will be the fifth seminar on this subject since 1976. These seminars have played an important role in fostering and promoting interactions between US and Japanese dermatologists and skin researchers. Because much information on the epidermis has become known since the last seminar in 1985, the proposed seminar is particularly timely. The epidermis covers the entire human body, protecting internal organs and maintaining human homeostasis. In order to perform protection and maintenance of proper homeostasis, the epidermis possesses highly organized features and functions. Much research has been undertaken to try to understand these, concentrating on defining the morphological and biochemical properties of the epidermis. The field is expanding rapidly, particularly in the areas of molecular biology and regulation of cell growth and differentiation. Significant contributions are currently being made to the field of skin science, which should eventually lead to the resolution of the pathogenesis of various skin diseases. Because the seminar will address topics where significant recent advances have been made, the meeting should bring the U.S. and Japanese research communities up to date and stimulate future collaborative projects.