The Ultracentrifuge as a Tool in Studies of Cell Function

一系列实验室练习正在开发中，这些练习将增强学生对细胞功能的理解。这些是对以前存在的细胞结构练习的补充。为了分离和提纯细胞成分，正在购买超速离心机和转子。该仪器名为Beckman TL-100，样品体积小，离心力高，可实现细胞成分的快速准确分离，使纯样品可在实验室期限内进行研究。这使得学生们有可能通过实验纯化的成分而不是通过低速离心机获得的粗馏分来探索细胞功能的分子机制。建议的练习将帮助学生理解我们是如何理解协调细胞过程的复杂相互作用的。学院将捐赠相当于该奖项的金额。

A series of lab exercises are being developed that will enhance the students' understanding of cell function. These complement previously existing exercises on cell structure. To isolate and purify cell components, an ultracentrifuge and rotors are being purchased. The instrument, the Beckman TL-100, has small sample volumes and high centrifugal forces to effect rapid and exact separations of cell constituents, making pure samples available for study within the time limit of a laboratory period. This makes it possible for the students to explore the molecular mechanisms of cell function by experimenting with purified components rather than crude fractions obtained by lower-speed centrifugations. The proposed exercises will help students understand how we have come to understand the complex interactions that coordinate cell processes. The college will contribute an amount equal to the award.