Photooxidations and Related Reactions

单线态氧与硫化物、次磺酸盐、烯丙基的反应 将研究锡烷和有机碲化合物。的 这项研究的结果将是三重：1）扩大 氧化反应的机理理解; 2） 开发利用新型氧化剂; 3)将提供新的合成的新底物的氧化 形成潜在有用材料的方法。在 在这项调查的过程中，邻近群体对 硫化物光氧化反应将进行研究，合成和 过磺酸和氢过氧硫烷的性质将是 检查，和能力，这些新的类别的氧化剂 将氧转移到杂原子和不饱和底物上， 被研究。 %%% 有机动力学计划的这笔赠款支持 爱德华·克莱南教授在牛津大学的持续工作 怀俄明州。分子氧可以暴露在高强度光下 在染料的存在下产生氧的激发态， 其被称为单线态氧。这种激发态物质 是一种短寿命的活性分子，它会氧化各种 有机分子在这个项目中， 将研究单线态氧与有机分子的反应。 此外，反应中产生的反应性中间体 这些氧化反应中的某些将用于转移氧原子， 以特定的方式与其他有机分子结合。这 在合成独特分子中的潜在应用。

Reactions of singlet oxygen with sulfides, sulfenates, allyl stannanes, and organotellurium compounds will be studied. The results of this research will be three-fold: 1) An expanded mechanistic understanding of oxidation reactions; 2) The development and utilization novel oxidizing agents; and 3) Oxidation of novel substrates that will provide new synthetic methods for the formation of potentially useful materials. In the course of this investigation, the effects of neighboring groups on sulfide photooxidations will be studied, the synthesis and properties of persulfenic acids and hydroperoxy sufuranes will be examined, and the ability of these new classes of oxidizing agents to transfer oxygen to heteroatoms and unsaturated substrates will be studied. %%% This grant from the Organic Dynamics Program supports the continuing work of Professor Edward Clennan at the University of Wyoming. Molecular oxygen can be exposed to high intensity light in the presence of a dye to generate an excited state of oxygen, which is referred to as singlet oxygen. This excited state species is a short-lived reactive molecule, which will oxidize various organic molecules. In this project, the detailed steps in the reaction of singlet oxygen with organic molecules will be studied. Furthermore, the reactive intermediates that are generated in certain of these oxidations will be used to transfer oxygen atoms to other organic molecules in a specific manner. This has potential application in the synthesis of unique molecules.