Synthesis of the Chlorophyll Isocyclic Ring

本提案的目的是研究 叶绿素等环 该提案具体旨在 了解镁-原卟啉单甲酯的环化反应。 催化该反应的酶系统具有两个 一种是可溶性的，一种是膜结合的。 这项研究将 试图分离和表征可溶性组分。 目标 研究的目的是尽可能地阐明 （二乙烯基）原叶绿酸在酶机制水平上， 以纯化系统的可溶性蛋白质组分， 用分子生物学分析问题的方法。

The purpose of this proposal is to study synthesis of the chlorophyll isocyclic ring. The proposal specifically seeks to understand the cyclization of Mg-protoporphyrin mono-methyl ester. The enzymological system catalyzing this reaction has two components, one soluble and one membrane-bound. This research will seek to isolate and characterize the soluble component. The aims are the research are to elucidate as far as possible the synthesis of (divinyl) protochlorophyllide at the level of enzyme mechanism, to purify the soluble protein component of the system and thus open the way for analysis of the problem by molecular biology.//