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Regulation of Carboxypeptidase in Mucor racemosus

Regulation of Carboxypeptidase in Mucor racemosus
总状毛霉羧肽酶的调控
批准号:
9106278
负责人:
David Logan
金额:
$21.5万
依托单位:
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
1991
资助国家:
美国
项目状态:
已结题
起止时间:
1991-09-15 至 1995-02-28

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中文摘要
翻译
真菌总状毛霉以酵母状和菌丝体的形式存在,这种二相性与其相关的几种蛋白酶活性似乎具有形态特异性。其中,一种名为CP3的丝氨酸羧肽酶是本研究的重点。该项目的目标包括克隆和鉴定决定这种蛋白质的结构基因,并分析该基因在快速形态发生过程中的细胞表达。从这些研究中可以更好地理解蛋白分解作为调节机制(S)在细胞代谢中的作用。
英文摘要
The fungus Mucor racemosus exists in both yeast-like and hyphal forms, and this dimorphism has associated with it several protease activities that appear morphology-specific. One of these, a serine carboxypeptidase termed CP3 is the focus of this research. The aims of the project include cloning and characterizing the structural gene that determines this protein, and to analyze the expression of that gene in cells undergoing rapid morphogenesis. The roles of proteolysis as regulatory mechanism(s) in cellular metabolism should be better understood from these studies.
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REU Site: Collaborative Research: Genomics and Computational Biology
  • 批准号:
    1427051
  • 项目类别:
    Continuing Grant
  • 资助金额:
    $16.1万
  • 财政年份:
    2014
  • 负责人:
    David Logan
  • 依托单位:
National Training Schools in Theoretical Chemistry, 2012 and 2014
  • 批准号:
    EP/J015091/1
  • 项目类别:
    Training Grant
  • 资助金额:
    $8.87万
  • 财政年份:
    2012
  • 负责人:
    David Logan
  • 依托单位:
CAA: Identification of Genetic Networks in Neurospora Crassa: A Systems Biology Approach
  • 批准号:
    0542915
  • 项目类别:
    Standard Grant
  • 资助金额:
    $15.71万
  • 财政年份:
    2006
  • 负责人:
    David Logan
  • 依托单位:
Mathematical Studies in Colloid Transport
  • 批准号:
    9708421
  • 项目类别:
    Standard Grant
  • 资助金额:
    $7.5万
  • 财政年份:
    1997
  • 负责人:
    David Logan
  • 依托单位:
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