Acquisition of a Data System for a Liquid Chromatograph/MassSpectrometer

液相色谱仪/质谱仪数据系统的采集

• 批准号: 9111391
• 负责人: Richard Van Breemen
• 金额: $ 4万
• 依托单位: North Carolina State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-03-15 至 1994-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9111391&HistoricalAwards=false
• 关键词: Acquisition; Data; System; Liquid; Chromatograph

A new data system is requested for a JEOL HX110HF double-focusing mass spectrometer, which is the only mass spectrometer in the Chemistry Department at N.C. State University. During the 1989- 1990 fiscal year, 1096 samples were analyzed in 2045 hours with this instrument. Approximately another 2000 hours were required to process and print the mass spectra, archive data files to magnetic tape, and restore data files to the disk drive for further data processing. During the last year, this instrument was equipped with a continuous-flow fast atom bombardment (FAB) interface and microbore HPLC system for liquid chromatography/mass spectrometry (LC/MS). In addition to the continued use of this mass spectrometer for routine service and research analyses of all types, LC/MS will be used by six major research groups and four minor users in seven departments within the University. Our experience over the last year has demonstrated that the slow data processing speed of the existing system limits the instrument and operator time available for data acquisition. Because 5 sec. computer reset time is required between scans, LC/MS chromatographic resolution is severely limited. The new data system will increase the sample throughput and productivity of the laboratory and permit the full performance of the LC/MS system to be realized.

JEOL HX 110HF双聚焦激光器需要一个新的数据系统 质谱仪，这是唯一的质谱仪在 北卡罗来纳大学化学系州立大学。 1989年- 1990财政年度，在2045小时内分析了1096份样品， 这个工具。 大约还需要2000小时， 处理和打印质谱图，将数据文件存档到磁 磁带，并将数据文件恢复到磁盘驱动器以获取更多数据 处理. 去年，该仪器配备了 具有连续流快速原子轰击（FAB）界面， 用于液相色谱/质谱的微孔HPLC系统 (LC/MS）。 除了继续使用这种质量 光谱仪，用于日常服务和研究分析 LC/MS将被六个主要研究小组和四个 大学内七个部门的小用户。 我们 过去一年的经验表明， 现有系统的处理速度限制了仪器， 操作员可用于数据采集的时间。 因为5秒。 扫描之间需要计算机重置时间，LC/MS 色谱分辨率受到严重限制。 新数据 系统将提高样品的吞吐量和生产力的 实验室和允许LC/MS系统的全面性能， 实现。