Acquisition of a Data System for a Liquid Chromatograph/MassSpectrometer

JEOL HX110HF双聚焦质谱仪是北卡罗来纳州立大学化学系唯一的质谱仪，需要一套新的数据系统。在1989- 1990财政年度，使用该仪器在2045小时内分析了1096个样本。处理和打印质谱，将数据文件归档到磁带，并将数据文件恢复到磁盘驱动器以进行进一步的数据处理，还需要大约2000小时。去年，该仪器配备了连续流快速原子轰击（FAB）界面和微孔HPLC系统，用于液相色谱/质谱分析（LC/MS）。除了继续使用该质谱仪进行日常服务和所有类型的研究分析外，LC/MS将被大学七个部门的六个主要研究小组和四个次要用户使用。我们去年的经验表明，现有系统缓慢的数据处理速度限制了仪器和操作员可用于数据采集的时间。由于扫描之间需要5秒的计算机复位时间，LC/MS色谱分辨率受到严重限制。新的数据系统将提高实验室的样品吞吐量和生产率，并使LC/MS系统的全部性能得以实现。

A new data system is requested for a JEOL HX110HF double-focusing mass spectrometer, which is the only mass spectrometer in the Chemistry Department at N.C. State University. During the 1989- 1990 fiscal year, 1096 samples were analyzed in 2045 hours with this instrument. Approximately another 2000 hours were required to process and print the mass spectra, archive data files to magnetic tape, and restore data files to the disk drive for further data processing. During the last year, this instrument was equipped with a continuous-flow fast atom bombardment (FAB) interface and microbore HPLC system for liquid chromatography/mass spectrometry (LC/MS). In addition to the continued use of this mass spectrometer for routine service and research analyses of all types, LC/MS will be used by six major research groups and four minor users in seven departments within the University. Our experience over the last year has demonstrated that the slow data processing speed of the existing system limits the instrument and operator time available for data acquisition. Because 5 sec. computer reset time is required between scans, LC/MS chromatographic resolution is severely limited. The new data system will increase the sample throughput and productivity of the laboratory and permit the full performance of the LC/MS system to be realized.