Positive and Negative Mechanisms Regulating Genes in Plant Defense

植物防御基因调节的正向和负向机制

• 批准号: 9118194
• 负责人: Mona Mehdy
• 金额: $ 26.08万
• 依托单位: University of Texas at Austin
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-04-01 至 1996-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9118194&HistoricalAwards=false
• 关键词: Positive; Negative; Mechanisms; Regulating; Genes

Transcriptional activation of genes during the defense response has been widely establish as a major level of regulation. However, the cis-elements and trans-acting factors involved in transcriptional activation have been characterized for only a few defense genes. In addition to positive regulation, there is also evidence for negative regulation of gene expression during the defense response. However, only 3 genes whose mRNAs are negatively regulated have been cloned and the cis elements and trans factors involved in their regulation are completely unknown. A major overall aim of this proposal is to identify and compare the mechanisms underlying the positive and negative regulation of genes involved in the defense response. A second major aim is to elucidate the mechanisms for the differential espression of the central phenylpropanoid and phytoalexin branch pathway genes.

防御反应过程中基因的转录激活 已被广泛确立为一个主要的监管层面。 但 转录调控中的顺式元件和反式作用因子 只有少数防御基因被激活。 除了积极的监管，还有证据表明， 在防御反应过程中基因表达的负调控。 然而，只有3个mRNA负调控的基因， 已克隆，并参与顺式元件和反式因子 他们的规则完全未知。 的一个主要总体目标 这一建议旨在确定和比较 基因的正向和负向调控参与了 防御反应。 第二个主要目的是阐明 中枢神经系统的差异表达机制 苯丙素和植物防御素分支途径基因。