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Biochemistry of the Ligninolytic Systems of Selected Fungi

选定真菌的木质素分解系统的生物化学

基本信息

批准号：
9121955
负责人：
T. Kent Kirk
金额：
$ 1.34万
依托单位：
University of Wisconsin-Madison
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
1992
资助国家：
美国
起止时间：
1992-06-01 至 1994-10-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=9121955&HistoricalAwards=false
关键词：
Biochemistry Ligninolytic Systems Selected Fungi

项目摘要

This Science in Developing Countries award will support the research collaboration of T. Kent Kirk of the University of Wisconsin and Rafael Vicuna of the Pontificia Universidad Catolica de Chile. The project aims to introduce fungal research into the Chilean investigator's laboratory, and to characterize the lignin-degrading enzyme system of unusual lignin- degrading fungi from Chile and the U.S. Through this project, the Chilean scientist will learn techniques for physiological, biochemical, and genetic studies with filamentous fungi. His will become the first laboratory in Chile with expertise in the molecular genetics of higher filamentous fungi, and one of the few working with these fungi in any capacity. One U.S. and two Chilean strains of lignin- degrading fungi will be studied. Enzymes they produce will be identified and characterized. Conditions for optimal enzyme production and efficient lignin mineralization will be determined. The investigators' past collaboration has shown that bacteria exert only minor action on polymeric lignin. Thus, the Chilean researcher now aims to focus on fungi. The ligninolytic fungi have substantial potential for practical applications in Chile and U.S., particularly for the paper pulping industry. Both the U.S. and Chilean sides will benefit from the basic information generated by their research.

该发展中国家科学奖将支持威斯康星大学的 T. Kent Kirk 和智利天主教大学的 Rafael Vicuna 的研究合作。该项目旨在将真菌研究引入智利研究人员的实验室，并表征来自智利和美国的不寻常木质素降解真菌的木质素降解酶系统。通过该项目，智利科学家将学习丝状真菌的生理、生化和遗传研究技术。他的实验室将成为智利第一个拥有高等丝状真菌分子遗传学专业知识的实验室，也是为数不多的以任何能力从事这些真菌工作的实验室之一。将研究一种美国菌株和两种智利菌株的木质素降解真菌。他们产生的酶将被鉴定和表征。将确定最佳酶生产和有效木质素矿化的条件。研究人员过去的合作表明，细菌对聚合木质素仅发挥很小的作用。因此，智利研究人员现在的目标是关注真菌。木质素分解真菌在智利和美国具有巨大的实际应用潜力，特别是在造纸工业中。美国和智利双方都将从其研究产生的基本信息中受益。