Near-Field Scanning Optical Microscopy for Chemical Analysis

用于化学分析的近场扫描光学显微镜

• 批准号: 9201185
• 负责人: George Morrison
• 金额: --
• 依托单位: Cornell University
• 依托单位国家: 美国
• 项目类别: Continuing grant
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-04-15 至 1996-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9201185&HistoricalAwards=false
• 关键词: Near; Field; Scanning; Optical; Microscopy

This research project, in the Analytical and Surface Chemistry Program, will develop the technique of Near Field Scanning Optical Microscopy for the characterization of the surface structure and chemistry of "soft" material surfaces. In addition to work on problems of instrument development, calibration of the scanning optical microscopy methodology will be carried out. Application of the method to a number of problems involving biological interfaces, membranes, and organic monolayers will be pursued. The development of a microscopic technique which can provide very high resolution structural information on these difficult surfaces, in combination with spatially resolved spectroscopic and chemical information, will have a very wide impact in the field of surface analysis and characterization. %%% The ability to characterize the structure of the surfaces of biological and macromolecular samples is crucial to the understanding of membrane processes and polymer properties. The research being carried out in this project will develop a promising new technique for the structural characterization of these "soft" material surfaces. This scanning optical microscopy method will have a great impact on the understanding of this important class of materials.

该研究项目属于分析和表面化学计划，将开发近场扫描光学显微镜技术，用于表征“软”材料表面的表面结构和化学。 除了解决仪器开发问题外，还将对扫描光学显微镜方法进行校准。 将寻求将该方法应用于涉及生物界面、膜和有机单层的许多问题。 显微技术的发展可以在这些困难表面上提供非常高分辨率的结构信息，结合空间分辨光谱和化学信息，将在表面分析和表征领域产生非常广泛的影响。 %%% 表征生物和大分子样品表面结构的能力对于理解膜过程和聚合物特性至关重要。 该项目正在进行的研究将开发一种有前途的新技术来表征这些“软”材料表面的结构。 这种扫描光学显微镜方法将对这一类重要材料的理解产生巨大影响。