Near-Field Scanning Optical Microscopy for Chemical Analysis

这个研究项目，在分析和表面化学 计划，将开发近场扫描技术 用于表面表征的光学显微镜 “软”材料表面的结构和化学性质。 在 除了关于仪器开发问题的工作外， 扫描光学显微镜方法的校准将 执行。 将该方法应用于一些 涉及生物界面、膜和 将采用有机单层。 的发展 一种可以提供非常高分辨率的显微技术 这些困难表面的结构信息， 结合空间分辨光谱和化学 信息，将在该领域产生非常广泛的影响， 表面分析和表征。 %%% 表征表面结构的能力 生物和大分子样品对 了解膜工艺和聚合物特性。 该项目正在进行的研究将开发一个 有前途的新技术的结构表征， 这些“软”材料表面。 这种扫描光学 显微镜的方法将有很大的影响， 这类重要的材料。

This research project, in the Analytical and Surface Chemistry Program, will develop the technique of Near Field Scanning Optical Microscopy for the characterization of the surface structure and chemistry of "soft" material surfaces. In addition to work on problems of instrument development, calibration of the scanning optical microscopy methodology will be carried out. Application of the method to a number of problems involving biological interfaces, membranes, and organic monolayers will be pursued. The development of a microscopic technique which can provide very high resolution structural information on these difficult surfaces, in combination with spatially resolved spectroscopic and chemical information, will have a very wide impact in the field of surface analysis and characterization. %%% The ability to characterize the structure of the surfaces of biological and macromolecular samples is crucial to the understanding of membrane processes and polymer properties. The research being carried out in this project will develop a promising new technique for the structural characterization of these "soft" material surfaces. This scanning optical microscopy method will have a great impact on the understanding of this important class of materials.