Biomedical Image Processing Laboratory

明尼苏达大学的生物医学图像处理实验室是一个计算资源，将为使用透射电子显微镜、扫描电子显微镜、共聚焦和常规光学显微镜的基础研究项目提供图像分析。该资源致力于研究和开发可用于阐明生物结构的方法，通过计算分析和重建大分子组装、细胞器和细胞的图像，通过不同的显微技术获得。此外，该中心将提供硬件和软件，以帮助正在研究的结构的三维表示。合作项目，如噬菌体形态发生和微管-tektin相互作用的研究，将利用正在开发的设施和方法。此外，该中心将为明尼苏达大学医学院的大量核心用户提供图像分析服务。该中心将为透射电子显微镜开发第二代在线图像分析系统，以及一种新型的低压场发射扫描电子显微镜图像分析系统。该中心还将利用许多不同形式的显微镜和成像产生类似问题和类似解决方案的事实。因此，其中一个领域的研究方法可以很容易地应用于本中心的其他领域。

The Biomedical Image Processing Laboratory at the University of Minnesota is a computational resource that will provide image analysis for basic research projects employing transmission electron microscopy, scanning electron microscopy, and confocal and conventional light microscopy. The resource is devoted to research and development in methods that can be used to elucidate biological structure by means of computational analysis and reconstruction of images of macromolecular assemblies, organelles and cells obtained by different microscopic techniques. In addition, the center will provide hardware and software to aid in the three-dimensional representation of the structures that are being studied. Collaborative projects, such as the study of bacteriophage morphogenesis and microtubule-tektin interactions, will take advantage of the facilities and the methods being developed. Further, the center will provide image analysis services to a large core of users at the University of Minnesota Medical School. The center will develop a second-generation on-line image analysis system for the transmission electron microscope, as well as a novel image analysis system for a low-voltage field-emission scanning electron microscope. The center will also take advantage of the fact that many different forms of microscopy and imaging generate similar problems and similar solutions. Thus, the research on methods within one of these areas may be easily applied to other areas within this center.