Symposium: Comparative Gastrointestinal Endocrinology: Integration of Function

研讨会:比较胃肠内分泌学:功能整合

基本信息

项目摘要

The gastrointestinal tract is a dynamic, chemosensory endocrine organ that integrates feeding behavior, digestion, absorption, and assimilation. This proposal requests support for a one day symposium to examine how that integration is mediated by hormones. Entitled "Comparative Gastrointestinal Endocrinology: Integration of Function," the symposium will be part of the American Society for Zoologists annual meeting held in Vancouver, B.C. in December 1992. The symposium has three objectives. First, the ten speakers will examine how the separate processes they investigate contribute to the regulation of the whole digestive system. Second, examples of the hormonal control of gut function will come from animal groups ranging from mammals to insects. Third, the symposium will emphasize hormone actions, rather than gut hormone chemistry. The outcome should lead to: 1) an evaluation of the integrative roles of regulatory factors for which functions are known; 2) strategies for determining the actions of "orphaned" chemical mediators, having known structures but unknown functions; 3) knowledge of interactions between gut peptides and hormones released at sites remote from the gut; and 4) an assessment of optimal biological models in nonmammalian vertebrates and invertebrates, for simplifying regularity complexity and for constructing the phylogeny of endocrine regulation.
胃肠道是一个动态的化学感受性内分泌系统 一个整合进食行为、消化、吸收和 同化该提案要求支持一天 研讨会,研究如何整合是由激素介导的。 比较胃肠内分泌学:整合 功能,“研讨会将是美国社会的一部分, 12月在不列颠哥伦比亚省温哥华举行的动物学家年会 1992.研讨会有三个目标。第一,十位发言人 将研究他们所研究的各个过程是如何 对整个消化系统的调节。第二,实例 肠道功能的激素控制将来自动物 从哺乳动物到昆虫。第三,研讨会将 强调激素作用,而不是肠道激素化学。的 结果应导致:1)对综合作用的评价 已知功能的调节因子; 2)策略 为了确定“孤儿”化学介质的作用, 已知结构但未知功能的; 3)了解 肠肽和激素之间的相互作用 远离肠道;和4)评估最佳生物学特性 非哺乳动物脊椎动物和无脊椎动物的模型, 简化规则复杂性,并构造 内分泌调节的遗传学。

项目成果

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