Acquisition of a Circular Dichroism Spectrometer

部分资金用于微处理器控制的可变- 温度，记录圆二色光谱仪， 所请求 该仪器将每天进行监督 主要研究者（Michael Y.小川）谁 将用它来确定 衍生用于电子转移的合成多肽 问题研究 该仪器还将广泛用于 联合首席研究员（N。B。Leontis）监测 新核酸结构的构象行为 例如三向DNA和RNA连接及其 与嵌入配体的相互作用。 此外该 仪器将由乔治布勒扬在使用 BGSU生物科学系监测 光合作用膜的结构转变。 轻微 化学系其他用户的项目 在BGSU和托莱多大学， 介绍了 没有可比较的仪器 在俄亥俄州西北部。

Partial funding for a microprocessor-controlled, variable- temperature, recording circular dichroism spectrometer is requested. The instrument will be supervised on a daily basis by the Principal Investigator (Michael Y. Ogawa) who will use it to determine the conformational behavior of synthetic polypepties derivatized for electron-transfer studies. The instrument will also be used extensively by the co-Principal Investigator (N. B. Leontis) to monitor the conformational behavior of novel nucleic acid structures such as three-way DNA and RNA junctions and their interactions with intercalating ligands. In addition, the instrument will be used by George Bullerjahn in the Department of Biological Sciences at BGSU to monitor structural transitions in photosynthetic membranes. Minor projects from other users in the Department of Chemistry at both BGSU and the University of Toledo are also described. There is no comparable instrumentation available in Northwest Ohio.