Phase Fluorometric Sensors

目前最先进的 生物过程测量是基于 过时的技术 新的通用 一种可以测量 分析物的数量，使用共同的 原则是非常必要的。 相 荧光测定法有望弥合这一点 基于一个简单的原则： 荧光团的寿命 响应分析物的变化， 其可以被测量为相位 探头时角度变化 强度调制激励 光 使用荧光寿命 （相位和调制） 该项目将 利用...的最新进展 化学，光学， 在线pH的电子学， 溶解氧、溶解碳 二氧化碳和葡萄糖传感 生物反应器

The current state-of-the-art for bioprocess measurements is based on dated technology. A new generic technology that can measure a number of analytes using a common principle is greatly needed. Phase fluorometry promises to bridge this gap based on a simple principle: a fluorophore exhibits a lifetime change in response to an analyte, which can be measured as a phase angle change when the probe is excited with intensity modulated light. Using fluorescence lifetime (phase and modulation) measurements, this project will exploit recent advances in chemistry, optics, and electronics for on-line pH, dissolved oxygen, dissolved carbon dioxide and glucose sensing in bioreactors.