Phase Fluorometric Sensors

这个项目是研究开发一类基于合成荧光团和相移荧光法的新型生物传感器。该方法使用的原理是，当被强度调制光束激发时，荧光团在其发射中响应于所讨论的分析物。这项研究将强调共振能量转移荧光团和可在高频调制的光源的发展。在线传感器pH值，氧气，二氧化碳和葡萄糖将开发和测试杂交细胞培养和微生物发酵。＊＊＊

9413262 Govind This project is on research to develop a new class of biosensors based on synthetic fluorophores and phase-shift fluorometry. The method uses the principle that a fluorophore exhibits shift in its emission in response to the analyte in question when excited by an intensity modulated beam of light. This research will stress the development of resonance energy transfer fluorophores and light sources that can be modulated at high frequencies. On-line sensors for pH, oxygen, carbon dioxide, and glucose will be developed and tested for both hybridoma cell cultures and microbial fermentations. ***