Finite Strain, Poroelastic Model for Large Arteries

大动脉有限应变、多孔弹性模型

• 批准号: 9210282
• 负责人: Bruce Simon
• 金额: $ 14.67万
• 依托单位: University of Arizona
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-08-15 至 1995-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9210282&HistoricalAwards=false
• 关键词: Finite; Strain; Poroelastic; Model; Large

This study will use a porohyperelastic model to study fluid transport, and in particular lipid transport, within the arterial wall. This model will include history-dependent finite deformation, stress, and transmural tissue fluid flow. Experimental studies will be used to verify and/or modify the model. The model that will be developed in this study is a step towards achieving a comprehensive arterial wall model that would help explain the etiology of atherosclerosis. The results could have an impact on the design of arterial vascular prostheses and be useful in the study of other tissues including cartilage and skin.

本研究将使用 孔隙超弹性模型研究 流体输送，特别是 脂质转运，在 动脉壁 这种模式的 包括历史相关有限 变形、应力和透壁 组织液流动 实验 研究将用于验证 和/或修改模型。 该模型将在 这项研究是朝着 实现全面的动脉 可以帮助解释 动脉粥样硬化的病因 结果可能会对 动脉血管设计 假体，并可用于 研究其他组织，包括 软骨和皮肤。