Carbanion, Carbocation, Carbenic, and Electron Transfer Initiated Mechanistic Studies

碳负离子、碳正离子、碳和电子转移引发的机理研究

• 批准号: 9213460
• 负责人: Xavier Creary
• 金额: $ 26.4万
• 依托单位: University of Notre Dame
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-08-01 至 1996-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9213460&HistoricalAwards=false
• 关键词: Carbanion; Carbocation; Carbenic; Electron; Transfer

This grant will provide support for the ongoing research program of Professor Xavier Creary at the University of Notre Dame. Kinetics, isotope effects, and product studies will be used to elucidate the mechanisms of organic reactions and to characterize reactive intermediates. Dihalodiazirines will be studied in order to provide evidence for the formation of a diaziryl anion intermediate. The possibility of a concerted cyclic elimination to give olefinic products under solvolysis conditions will be explored. Silyl substituted carbenes will also be synthesized and the migratory aptitude of silicon determined. %%% The intimate details of several important reactions that transform carbon containing molecules into new and interesting molecules will be determined. Independent synthesis of the suggested reaction intermediates in these important transformations will allow unambiguous evidence for their involvement. The possibility that the transfer of an electron will trigger some of these transformations will be examined by careful analysis of the reaction mixtures. It is anticipated that the results of this study will provide the basis for predicting the outcome of many reactions.

这笔赠款将为正在进行的研究提供支持 诺特尔大学的泽维尔·克里里教授 夫人 动力学、同位素效应和产品研究将在 用于阐明有机反应的机理， 表征活性中间体。 二卤二氮丙啶将是 研究，以提供证据的形成， 二氮杂丙烯基阴离子中间体。 一个联合的可能性 在溶剂分解下循环消除得到烯属产物 条件将进行探索。 甲硅烷基取代的卡宾将 硅的迁移能力 测定 %%% 几个重要反应的细节， 将含碳分子转化成新的有趣的 分子将被确定。 独立合成的 在这些重要的反应中， 转换将允许明确的证据， 参与。 一个电子的转移 将触发其中的一些转变， 仔细分析反应混合物。 预计 这项研究的结果将为 预测许多反应的结果。