Chemistry of Iridium Hydride Complexes Synthesized by Addition of Non-Metal Hydrides

非金属氢化物加成合成氢化铱配合物的化学

• 批准号: 9214027
• 负责人: Joseph Merola
• 金额: $ 26.7万
• 依托单位: Virginia Polytechnic Institute and State University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-08-01 至 1997-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9214027&HistoricalAwards=false
• 关键词: Chemistry; Iridium; Hydride; Complexes; Synthesized

This award in the Inorganic, Bioinorganic, and Organometallic Chemistry Program supports research by Dr. Joseph S. Merola of the Chemistry Department, Virginia Polytechnic Institute, on oxidation addition reactions of various organic substrates to iridium phosphine complexes. The substrates involve E-H bonds, where E = H,B,C,N,O. The reaction chemistry of the series of E-Ir-H compounds thus generated will be investigated, especially with respect to the insertion of unsaturated molecules into the E-Ir and H-Ir bonds. Thus, fundamental processes occurring at the metal center in chemistry related to hydrogenation, catalytic hydroboration, C-H bond activation, hydroamination, and hydroalkoxlylation will be studied. Anionic groups on the iridium will be varied in order to promote the catalytic activity of these systems. Some of the reactions will be carried out in aqueous solution. %%% Oxidation addition reactions play an important role in both catalytic and stoichiometric reaction chemistry of organometallic compounds. The long range goal of this project is to develop catalyst systems for the addition of E-H bonds to unsaturated organic compounds. This could have important industrial implications but since the reaction chemistry of these potentially significant processes is not well known, fundamental advances are also anticipated.

该奖项属于无机、生物无机和有机金属化学项目，用于支持弗吉尼亚理工学院化学系的 Joseph S. Merola 博士关于各种有机底物与铱膦配合物的氧化加成反应的研究。 底物涉及 E-H 键，其中 E = H、B、C、N、O。 将研究由此产生的一系列 E-Ir-H 化合物的反应化学，特别是关于不饱和分子插入 E-Ir 和 H-Ir 键的反应。 因此，将研究与氢化、催化硼氢化、C-H键活化、加氢胺化和加氢烷氧基化相关的化学中金属中心发生的基本过程。 铱上的阴离子基团将发生变化，以促进这些系统的催化活性。 一些反应将在水溶液中进行。 %%% 氧化加成反应在有机金属化合物的催化和化学计量反应化学中发挥着重要作用。 该项目的长期目标是开发用于向不饱和有机化合物添加 E-H 键的催化剂系统。 这可能具有重要的工业意义，但由于这些潜在重要过程的反应化学尚不清楚，因此预计也会取得根本性进展。