Natural Products from Peruvian Wound-Healing Plants

来自秘鲁伤口愈合植物的天然产品

• 批准号: 9221270
• 负责人: Gerald Hammond
• 金额: $ 1.36万
• 依托单位: University of Massachusetts, Dartmouth
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-01-01 至 1995-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9221270&HistoricalAwards=false
• 关键词: Natural; Products; Peruvian; Wound; Healing

This award will support a collaborative research project between Dr. Gerald P. Hammond, of the University of Massachusetts, Dartmouth and Dr. Abraham J. Vaisberg, of the Institute of Tropical Medicine Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Peru. The research involves the isolation and structure elucidation of bioactive compounds from Peruvian wound-healing plants. Plants extracts will be bioassayed for wound healing activity and screened for other pharmacological effects. Samples will be assayed for cell migration and cell proliferation, and will be fractioned until pure bioactive compounds are obtained. The bioactive compounds thus obtained will be evaluated for their biological properties. This collaborative research fulfills the program objective of advancing scientific knowledge by combining the complementary expertise of researchers from both countries in an area of strong mutual interest. Proving the medicinal or scientific value of these plants will contribute to the preservation of folk medicine practices and to the conservation of biological diversity.

该奖项将支持马萨诸塞大学达特茅斯分校的杰拉尔德·P·哈蒙德博士和热带医学研究所的亚伯拉罕·J·维斯伯格博士之间的合作研究项目，佩鲁亚纳·卡耶塔诺大学，秘鲁。这项研究涉及从秘鲁伤口愈合植物中分离和结构鉴定生物活性化合物。将对植物提取物进行伤口愈合活性的生物测试，并筛选其他药理作用。样品将被检测细胞迁移和细胞增殖，并将被分离，直到获得纯粹的生物活性化合物。这样得到的生物活性化合物将被评估它们的生物学特性。这项合作研究通过结合两国研究人员在共同感兴趣的领域的互补专业知识来实现促进科学知识的计划目标。证明这些植物的药用或科学价值将有助于保存民间医药做法和保护生物多样性。