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Arabidopsis DNA Methylation Mutants

Arabidopsis DNA Methylation Mutants
拟南芥 DNA 甲基化突变体
批准号:
9306266
负责人:
Eric Richards
金额:
$34.5万
依托单位:
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
1993
资助国家:
美国
项目状态:
已结题
起止时间:
1993-08-01 至 1997-01-31

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9306266 Richards Post-replicative methylation is the most common DNA modification present in eukaryotic cells. Although DNA methylation has been the subject of intense study, many questions remain about the function of this form of DNA modification in eukaryotes. The proposal outlines a genetic approach to the study of DNA methylation using the flowering plant Arabidopsis thaliana as a model. We have isolated A. thaliana mutants that contain reduced levels of cytosine methylation. Plans for further characterization of these hypomethylation mutants and strategies for isolating new methylation mutants are proposed. %%% It is anticipated that the A. thaliana mutants will provide a new system for studying eukaryotic DNA methylation. ***
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URoL: Epigenetics 1: Genomic and epigenetic determinants of nuclear morphology and mechanics
Genetic Instability at a Complex Gene Cluster in Arabidopsis
Epigenetic Variation in the Arabidopsis Genome
Epigenetic Variation in the Arabidopsis Genome
  • 批准号:
    0548597
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  • 财政年份:
    2006
  • 负责人:
    Eric Richards
  • 依托单位:
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