Arabidopsis DNA Methylation Mutants
Arabidopsis DNA Methylation Mutants
批准号:
9604972
负责人:
Eric Richards
金额:
$39.2万
依托单位:
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
1997
资助国家:
美国
项目状态:
已结题
起止时间:
1997-03-01 至 2000-02-29
中文摘要
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英文摘要
9604972 Richards Technical Mutants of Arabidopsis thaliana which have a decrease in DNA methylation (ddm) were isolated and characterized earlier. The ddml mutant has only about 30% of the wild type methylcytosine although it has wild type levels of methyl transferase. Moreover, it has been found that if these mutants are continuously selfed, progressive abnormalities appear. One such abnormality was reduced plant size and apical dominance (ball). The ball mutation, which is stable, has been mapped to a genome site different than the ddml mutation. During the tenure of this project, the DDMl gene will be isolated and characterized. Additionally, the BAL locus will be isolated by a map-based cloning approach and characterized at a molecular level. The phenotypic, genetic, biochemical and molecular analysis of ddm2 mutants will also continue. Non-technical It has been observed that there are described genetic phenomena which cannot be explained by Mendelian genetics and suggestive evidence implicates DNA methylation. It has been difficult to document cause and effect but the information resulting from this work should provide greater insiqht into basic qenetic mechanisms.
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URoL: Epigenetics 1: Genomic and epigenetic determinants of nuclear morphology and mechanics
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批准号:2022048
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项目类别:Continuing Grant
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资助金额:$50.0万
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财政年份:2020
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负责人:Eric Richards
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依托单位:
Genetic Instability at a Complex Gene Cluster in Arabidopsis
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批准号:1158297
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项目类别:Continuing Grant
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资助金额:$61.44万
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财政年份:2012
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负责人:Eric Richards
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依托单位:
Epigenetic Variation in the Arabidopsis Genome
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批准号:0956820
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项目类别:Continuing Grant
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资助金额:$12.54万
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财政年份:2008
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负责人:Eric Richards
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依托单位:
Epigenetic Variation in the Arabidopsis Genome
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批准号:0548597
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项目类别:Continuing Grant
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资助金额:$41.39万
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财政年份:2006
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负责人:Eric Richards
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依托单位:
Epigenetic Variation and Inheritance
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批准号:0321990
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项目类别:Standard Grant
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资助金额:$34.61万
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财政年份:2003
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负责人:Eric Richards
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依托单位:
13th International Conference on Arabidopsis Research; June 28 - July 2, 2002, Seville, Spain
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批准号:0224881
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项目类别:Standard Grant
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资助金额:$3.0万
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财政年份:2002
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负责人:Eric Richards
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依托单位:
Conference: Seventh FASEB Summer on 'Mechanisms in Plant Development'
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批准号:0078115
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项目类别:Standard Grant
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资助金额:$1.0万
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财政年份:2000
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负责人:Eric Richards
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依托单位:
Arabidopsis DDM1: DNA Methylation and Epigenetic Stability
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批准号:9985348
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项目类别:Continuing Grant
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资助金额:$46.5万
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财政年份:2000
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负责人:Eric Richards
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依托单位:
Arabidopsis DNA Methylation Mutants
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批准号:9306266
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项目类别:Continuing Grant
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资助金额:$34.5万
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财政年份:1993
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负责人:Eric Richards
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依托单位:
Characterization of Arabidopsis Telomeres
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批准号:8905580
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项目类别:Continuing Grant
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资助金额:$9.5万
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财政年份:1989
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负责人:Eric Richards
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依托单位:
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