RPG: Neuroethological Basis of Hygienic Behavior in Honey Bees

RPG：蜜蜂卫生行为的神经行为学基础

• 批准号: 9307026
• 负责人: Marla Spivak
• 金额: $ 1.8万
• 依托单位: University of Minnesota-Twin Cities
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-07-01 至 1995-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9307026&HistoricalAwards=false
• 关键词: RPG; Neuroethological; Basis; Hygienic; Behavior

This is a research planning grant for women. Hygienic behavior is considered the primary mechanism of resistance to at least two disease deleterious to larval honey bees, American foulbrood caused by the bacterium Bacillus larvae and chalkbrood caused by the fungus Ascosphaera apis. Resistance is conferred by hygienic bees detecting, uncapping, and removing diseased brood from the nest before the causative organism reaches the infectious stage. The objectives of the research planning activities are to 1) continue selection and maintenance of hygienic and non-hygienic lines of honey bees; 2) continue development of a more precise and realistic behavioral assay of hygienic behavior; 3) analyze the behavioral response of individual hygienic and non-hygienic bees to sealed cells containing freeze-killed brood and to cells containing larvae infected with A. apis; and 4) explore whether the behaviors exhibited by hygienic and non-hygienic bees are associated with a differential distribution of biogenic amines in the bee brain. Biogenic amines may control the behavioral states and therefore, the response to diseased brood, of the genetically distinct lines of bees. The goals of this research are to explore the ethological and neurobiological bases for the expression of hygienic and non- hygienic behavior and to assess the role of these behaviors in disease resistance in honey bees. Hygienic behavior can control economically important diseases of honey bees, however its expression appears to be facultative. It is crucial to study the relation between the genetic, environmental, behavioral, and neural factors that regulate the expressions of both hygienic and non- hygienic behaviors to understand how the balanced expressions of these factors may confer resistance to diseases. An analysis of the neuroethological mechanisms underlying the behaviors will provide an opportunity to examine how behavioral states may affect the expression of genetically determined behaviors.

这是一项针对妇女的研究规划补助金。 不道德行为是 被认为是对至少两种 对蜜蜂幼虫有害的一种疾病，由美洲蜜蜂幼虫的腐臭引起 由细菌芽孢杆菌幼虫和白垩病引起的 蜜蜂囊腔菌 卫生蜜蜂赋予抵抗力 发现、揭开并从巢中移走患病的幼仔 在致病微生物达到感染阶段之前。 的 研究规划活动的目标是：（1）继续 卫生和非卫生生产线的选择和维护 蜜蜂; 2）继续发展更精确和更现实的 卫生行为行为分析 个体卫生蜂和非卫生蜂对密封的反应 含有冷冻杀死的幼仔的细胞和含有幼虫的细胞 方式感染4）探索行为是否 卫生和不卫生的蜜蜂所表现出的 生物胺在蜜蜂脑中的不同分布。 生物胺可以控制行为状态，因此， 不同基因品系对疾病育雏的反应 蜜蜂。 本研究的目的是探讨行为学和 神经生物学基础的表达卫生和非 卫生行为，并评估这些行为在 蜜蜂的抗病能力 肥胖行为可以控制 蜜蜂的重要经济疾病，然而， 表达似乎是任意的。 关键是要研究 遗传、环境、行为和神经之间的关系 规范卫生和非卫生的表达的因素， 卫生行为，以了解如何平衡的表达， 这些因素可赋予对疾病的抗性。 分析 行为背后的神经行为学机制将 提供了一个机会来研究行为状态如何影响 基因决定的行为的表达。