Stereochemistry of Nanomolecules

将在三个相关领域开展研究。在第一部分中， 杂三角烯将被用作构建单元， 纳米结构。这些分子量超过1000 将对包合物的道尔顿进行研究 形成，极化率和电子转移，涉及 π芳族体系。在第二部分中，拓扑地 将合成立体异构的Enhancement网络，其 结构基于图论。第三部分 碗状多环芳烃的合成将 完成了碗对碗倒置的动力学将是 通过动态核磁共振光谱学研究。这些化合物的衍生物 将偶联形成与富勒烯有关的大环番 片段 %%% 有机动力学计划的这笔赠款支持以下工作： Jay S.西格尔在加州大学圣地亚哥分校。 大分子将被合成， 蛀牙将其他分子包含在这些空腔中将是 以及分子内的相互作用， 通过光谱检测。碗状的大分子将被 准备并确定碗到碗的倒置屏障 通过光谱方法。这些碗状的分子也会 偶联产生与富勒烯有关的片段，最近， 发现了碳的同素异形体。最后，分子将 原子链被包围的地方合成的。的特定 包围模式是基于图论，一个数学 纪律

Research in three related areas will be pursued. In the first part, heterotriangulenes will be used as building blocks for nanostructures. These molecules with molecular weights of over 1000 Daltons will be investigated with regard to inclusion compound formation, and polarizability and electron-transfer involving the pi-aromatic systems. In the second part, topologically stereoisomeric entwined networks will be synthesized, whose structures are based on graph theory. In the third part, the synthesis of bowl-shaped polycyclic aromatic hydrocarbons will accomplished. The dynamics of the bowl-to-bowl inversion will be studied by dynamic NMR spectroscopy. Derivatives of these compounds will be coupled to form macrocyclophanes related to fullerene fragments. %%% This grant from the Organic Dynamics Program supports the work of Professor Jay S. Siegel at the University of California, San Diego. Large molecules will be synthesized which contain internal cavities. Inclusion of other molecules into these cavities will be studied as well as the intramolecular interactions which will be detected spectroscopically. Bowl-shaped large molecules will be prepared and the bowl-to-bowl inversion barrier will be determined by spectroscopic methods. These bowl-shaped molecules will also be coupled to produce fragments related to fullerene, a recently discovered allotrope of carbon. Finally, molecules will be synthesized where chains of atoms become entwined. The particular entwined pattern is based on graph theory, a mathematical discipline.