Stereochemistry of Nanomolecules

纳米分子的立体化学

• 批准号: 9628565
• 负责人: Jay Siegel
• 金额: $ 46.25万
• 依托单位: University of California-San Diego
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-07-01 至 2000-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9628565&HistoricalAwards=false
• 关键词: Stereochemistry; Nanomolecules

With funding from the Organic Dynamics Program, Professor Siegel of the Department of Chemistry at the University of California--San Diego will investigate the chemistry of three nanomolecular morphologies. The focus of this work is the computational design, synthesis and characterization of Stem-Palmate Clusters, Entwined Networks of Cyclophanes, and Aromatic Shells and Curved Surfaces. Particular attention is to be paid to the stereochemical characteristics of the above systems. New synthetic materials developed in chemical laboratories range in size from a small (10 angstrom) molecules to very large compounds such as polymers that are 100 angstroms long. This investigation focuses on intermediate systems referred to as nanomolecules (10-100 angstoms). Computer aided design followed by synthesis will provide a myriad of molecular motifs that are useful in biosensors, optical materials and liquid crystals. The three dimensional character of these systems is of particular importance.

在有机动力学项目的资助下，加州大学圣地亚哥分校化学系的西格尔教授将研究三种纳米分子形态的化学性质。这项工作的重点是计算设计，合成和表征茎-棕榈簇，环烷缠绕网络，芳香壳和曲面。要特别注意上述体系的立体化学特性。化学实验室开发的新合成材料的大小不等，小到10埃的小分子，大到100埃长的聚合物。本研究的重点是被称为纳米分子（10-100埃）的中间系统。计算机辅助设计和合成将为生物传感器、光学材料和液晶提供大量有用的分子基序。这些系统的三维特性特别重要。